2009

2008

• Vaidya VS, Waikar SS, Ferguson MA, Collings FB, Sunderland K, Gioules C, Bradwin G, Matsouaka R, Betensky RA, Curhan GC, Bonventre JV. Urinary biomarkers for sensitive and specific detection of acute kidney injury in humans. Clin Transl Sci. 2008 Dec;1(3):200-8. doi: 10.1111/j.1752-8062.2008.00053.x. PMID: 19212447; PMCID: PMC2638059

 

• Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer’s disease. Nat Neurosci. 2008 Nov;11(11):1311-8. doi: 10.1038/nn.2213. Epub 2008 Oct 19. PMID: 18931664; PMCID: PMC2597064

 

• Chagnon F, Vaidya VS, Plante GE, Bonventre JV, Bernard A, Guindi C, Lesur O. Modulation of aquaporin-2/vasopressin2 receptor kidney expression and tubular injury after endotoxin (lipopolysaccharide) challenge. Crit Care Med. 2008 Nov;36(11):3054-61. doi: 10.1097/CCM.0b013e318186a938. PMID: 18824919; PMCID: PMC2745282

 

• Waanders F, Vaidya VS, van Goor H, Leuvenink H, Damman K, Hamming I, Bonventre JV, Vogt L, Navis G. Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trial. Am J Kidney Dis. 2009 Jan;53(1):16-25. doi: 10.1053/j.ajkd.2008.07.021. Epub 2008 Sep 27. PMID:18823687; PMCID: PMC3298772

 

• Trujillo J, Cruz C, Tovar A, Vaidya V, Zambrano E, Bonventre JV, Gamba G, Torres N, Bobadilla NA. Renoprotective mechanisms of soy protein intake in the obese Zucker rat. Am J Physiol Renal Physiol. 2008 Nov;295(5):F1574-82. doi: 10.1152/ajprenal.90385.2008. Epub 2008 Sep 24. PMID: 18815216; PMCID: PMC4747908

 

• Waikar SS, Bonventre JV. Biomarkers for the diagnosis of acute kidney injury. Nephron Clin Pract. 2008;109(4):c192-7. doi: 10.1159/000142928. Epub 2008 Sep 18. PMID: 18802367; PMCID: PMC2713682

 

• Bonventre JV. Kidney Injury Molecule-1 (KIM-1): a specific and sensitive biomarker of kidney injury. Scand J Clin Lab Invest Suppl. 2008;241:78-83. doi: 10.1080/00365510802145059. PMID: 18569971

 

• Taylor AL, Bonventre JV, Uliasz TF, Hewett JA, Hewett SJ. Cytosolic phospholipase A2 alpha inhibition prevents neuronal NMDA receptor-stimulated arachidonic acid mobilization and prostaglandin production but not subsequent cell death. J Neurochem. 2008 Aug;106(4):1828-40. doi: 10.1111/j.1471-4159.2008.05527.x. Epub 2008 Jun 28. PMID: 18564366; PMCID: PMC2582587

 

• Bonventre JV. Dialysis in acute kidney injury–more is not better. N Engl J Med. 2008 Jul 3;359(1):82-4. doi: 10.1056/NEJMe0803765. Epub 2008 May 20. PMID:18492868

 

• Zhang J, Brown RP, Shaw M, Vaidya VS, Zhou Y, Espandiari P, Sadrieh N, Stratmeyer M, Keenan J, Kilty CG, Bonventre JV, Goering PL. Immunolocalization of Kim-1, RPA-1, and RPA-2 in kidney of gentamicin-, mercury-, or chromium-treated rats: relationship to renal distributions of iNOS and nitrotyrosine. Toxicol Pathol. 2008 Apr;36(3):397-409. doi: 10.1177/0192623308315832. Epub 2008. Apr 25. PMID: 18441258; PMCID: PMC2745064

 

• Ichimura T, Asseldonk EJ, Humphreys BD, Gunaratnam L, Duffield JS, Bonventre JV. Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells. J Clin Invest. 2008May;118(5):1657-68. doi: 10.1172/JCI34487. PMID: 18414680;  PMCID: PMC2293335

 

• Humphreys BD, Valerius MT, Kobayashi A, Mugford JW, Soeung S, Duffield JS, McMahon AP, Bonventre JV. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2008 Mar 6;2(3):284-91. doi: 10.1016/j.stem.2008.01.014. PMID: 18371453

 

• Ferguson MA, Vaidya VS, Bonventre JV. Biomarkers of nephrotoxic acute kidney injury. Toxicology. 2008 Mar 20;245(3):182-93. doi: 10.1016/j.tox.2007.12.024. Epub 2008 Jan 4. PMID: 18294749; PMCID: PMC4038970

 

• Murray PT, Devarajan P, Levey AS, Eckardt KU, Bonventre JV, Lombardi R, Herget-Rosenthal S, Levin A. A framework and key research questions in AKI diagnosis and staging in different environments. Clin J Am Soc Nephrol. 2008 nMay;3(3):864-8. doi: 10.2215/CJN.04851107. Epub 2008 Feb 20. PMID: 18287251

 

• Lock EA, Bonventre JV. Biomarkers in translation; past, present and future. Toxicology. 2008 Mar 20;245(3):163-6. doi: 10.1016/j.tox.2007.12.004. Epub 2007 Dec 17. PMID: 18272278

 

• Cubells L, Vilà de Muga S, Tebar F, Bonventre JV, Balsinde J, Pol A, Grewal T, Enrich C. Annexin A6-induced inhibition of cytoplasmic phospholipase A2 is linked to caveolin-1 export from the Golgi. J Biol Chem. 2008 Apr 11;283(15):10174-83. doi: 10.1074/jbc.M706618200. Epub 2008 Feb 1. PMID: 18245088

 

• Zhang PL, Rothblum LI, Han WK, Blasick TM, Potdar S, Bonventre JV. Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury. Kidney Int. 2008 Mar;73(5):608-14. doi: 10.1038/sj.ki.5002697. Epub 2007 Dec 26. PMID: 18160964; PMCID: PMC2915578

 

• Noor S, Goldfine H, Tucker DE, Suram S, Lenz LL, Akira S, Uematsu S, Girotti M, Bonventre JV, Breuel K, Williams DL, Leslie CC. Activation of cytosolic phospholipase A2alpha in resident peritoneal macrophages by Listeria monocytogenes involves listeriolysin O and TLR2. J Biol Chem. 2008 Feb 22;283(8):4744-55. doi: 10.1074/jbc.M709956200. Epub 2007 Dec 14. PMID: 18083708; PMCID: PMC4741307

 

• Han WK, Waikar SS, Johnson A, Betensky RA, Dent CL, Devarajan P, Bonventre JV. Urinary biomarkers in the early diagnosis of acute kidney injury. Kidney Int. 2008 Apr;73(7):863-9. doi: 10.1038/sj.ki.5002715. Epub 2007 Dec 5. Erratum in: Kidney Int. 2009 Aug;76(3):348-9. PMID: 18059454; PMCID: PMC2586909

 

• Bonventre JV. Urine neutrophil gelatinase-associated lipocalin as a marker of acute kidney injury in critically ill children. Nat Clin Pract Nephrol. 2008 Feb;4(2):78-9. doi: 10.1038/ncpneph0677. Epub 2007 Nov 27. PMID: 18043593

 

• Vaidya VS, Ferguson MA, Bonventre JV. Biomarkers of acute kidney injury. Annu Rev Pharmacol Toxicol. 2008;48:463-93. doi: 10.1146/annurev.pharmtox.48.113006.094615. PMID: 17937594; PMCID: PMC2742480

 

• Zhou Y, Vaidya VS, Brown RP, Zhang J, Rosenzweig BA, Thompson KL, Miller TJ, Bonventre JV, Goering PL. Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium. Toxicol Sci. 2008 Jan;101(1):159-70. doi: 10.1093/toxsci/kfm260. Epub 2007 Oct 13. PMID: 17934191; PMCID: PMC2744478

 

• Humphreys BD, Bonventre JV. Mesenchymal stem cells in acute kidney injury. Annu Rev Med. 2008;59:311-25. doi: 10.1146/annurev.med.59.061506.154239. PMID: 17914926

2007

• Lock EA, Bonventre JV. Biomarkers in translation; past, present and future. Toxicology. 2008 Mar 20;245(3):163-6. doi: 10.1016/j.tox.2007.12.004. Epub 2007 Dec 17. PMID: 18272278

 

• van Timmeren MM, Vaidya VS, van Ree RM, Oterdoom LH, de Vries AP, Gans RO,  van Goor H, Stegeman CA, Bonventre JV, Bakker SJ. High urinary excretion of kidney injury molecule-1 is an independent predictor of graft loss in renal transplant recipients. Transplantation. 2007 Dec 27;84(12):1625-30. doi: 10.1097/01.tp.0000295982.78039.ef. PMID: 18165774; PMCID: PMC2745062

 

• Waikar SS, Bonventre JV. Biomarkers for the diagnosis of acute kidney injury. Curr Opin Nephrol Hypertens. 2007 Nov;16(6):557-64. doi: 10.1097/MNH.0b013e3282f08745. PMID: 18089971

 

• Zhang Z, Humphreys BD, Bonventre JV. Shedding of the urinary biomarker kidney injury molecule-1 (KIM-1) is regulated by MAP kinases and juxtamembrane region. J Am Soc Nephrol. 2007 Oct;18(10):2704-14. doi: 10.1681/ASN.2007030325. PMID: 17898236

 

• Muñoz NM, Meliton AY, Arm JP, Bonventre JV, Cho W, Leff AR. Deletion of secretory group V phospholipase A2 attenuates cell migration and airway hyperresponsiveness in immunosensitized mice. J Immunol. 2007 Oct 1;179(7):4800-7. doi: 10.4049/jimmunol.179.7.4800. PMID: 17878379

 

• Hentschel DM, Mengel M, Boehme L, Liebsch F, Albertin C, Bonventre JV,Haller H, Schiffer M. Rapid screening of glomerular slit diaphragm integrity in larval zebrafish. Am J Physiol Renal Physiol. 2007 Nov;293(5):F1746-50. doi: 10.1152/ajprenal.00009.2007. Epub 2007 Aug 15. PMID: 17699558

 

• Prozialeck WC, Vaidya VS, Liu J, Waalkes MP, Edwards JR, Lamar PC, Bernard. AM, Dumont X, Bonventre JV. Kidney injury molecule-1 is an early biomarker of cadmium nephrotoxicity. Kidney Int. 2007 Oct;72(8):985-93. doi: 10.1038/sj.ki.5002467. Epub 2007 Aug 8. PMID: 17687258; PMCID: PMC2747605

 

• Chen G, Bridenbaugh EA, Akintola AD, Catania JM, Vaidya VS, Bonventre JV, Dearman AC, Sampson HW, Zawieja DC, Burghardt RC, Parrish AR. Increased susceptibility of aging kidney to ischemic injury: identification of candidate genes changed during aging, but corrected by caloric restriction. Am J Physiol Renal Physiol. 2007 Oct;293(4):F1272-81. doi: 10.1152/ajprenal.00138.2007. Epub 2007 Aug 1. PMID: 17670906; PMCID: PMC2758575

 

• Espandiari P, Zhang J, Rosenzweig BA, Vaidya VS, Sun J, Schnackenberg L, Herman EH, Knapton A, Bonventre JV, Beger RD, Thompson KL, Hanig J. The utility of a rodent model in detecting pediatric drug-induced nephrotoxicity. Toxicol Sci. 2007 Oct;99(2):637-48. doi: 10.1093/toxsci/kfm184. Epub 2007 Jul 17. PMID: 17636248; PMCID: PMC2729403

 

• Bonventre JV. Diagnosis of acute kidney injury: from classic parameters to new biomarkers. Contrib Nephrol. 2007;156:213-9. doi: 10.1159/000102086. PMID: 17464130.

 

• Bonventre JV. Pathophysiology of acute kidney injury: roles of potential inhibitors of inflammation. Contrib Nephrol. 2007;156:39-46. doi: 10.1159/000102069. PMID: 17464114.

 

• Humphreys BD, Bonventre JV. The contribution of adult stem cells to renal repair. Nephrol Ther. 2007 Mar;3(1):3-10. doi: 10.1016/j.nephro.2006.12.002. Epub 2007 Feb 22. PMID: 17383586

 

• Kikawada E, Bonventre JV, Arm JP. Group V secretory PLA2 regulates TLR2-dependent eicosanoid generation in mouse mast cells through amplification of ERK and cPLA2alpha activation. Blood. 2007 Jul 15;110(2):561-7. doi: 10.1182/blood-2006-10-052258. Epub 2007 Mar 16. PMID: 17369491; PMCID: PMC1924482

 

• Lin F, Zhang PL, Yang XJ, Shi J, Blasick T, Han WK, Wang HL, Shen SS, Teh BT, Bonventre JV. Human kidney injury molecule-1 (hKIM-1): a useful immunohistochemical marker for diagnosing renal cell carcinoma and ovarian clear cell carcinoma. Am J Surg Pathol. 2007 Mar;31(3):371-81. Doi 10.1097/01.pas.0000213353.95508.67. PMID: 17325478

 

• Ghosh M, Loper R, Ghomashchi F, Tucker DE, Bonventre JV, Gelb MH, Leslie CC. Function, activity, and membrane targeting of cytosolic phospholipase A(2)zeta in mouse lung fibroblasts. J Biol Chem. 2007 Apr 20;282(16):11676-86. doi: 10.1074/jbc.M608458200. Epub 2007 Feb 11. PMID: 17293613; PMCID: PMC2678067

 

• Liangos O, Perianayagam MC, Vaidya VS, Han WK, Wald R, Tighiouart H, MacKinnon RW, Li L, Balakrishnan VS, Pereira BJ, Bonventre JV, Jaber BL. Urinary N-acetyl-beta-(D)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure. J Am Soc Nephrol. 2007 Mar;18(3):904-12. doi: 10.1681/ASN.2006030221. Epub 2007 Jan 31. PMID:  17267747

 

• Perianayagam MC, Liangos O, Kolyada AY, Wald R, MacKinnon RW, Li L, Rao M, Balakrishnan VS, Bonventre JV, Pereira BJ, Jaber BL. NADPH oxidase p22phox and catalase gene variants are associated with biomarkers of oxidative stress and adverse outcomes in acute renal failure. J Am Soc Nephrol. 2007 Jan;18(1):255-63. doi: 10.1681/ASN.2006070806. Epub 2006 Dec 6. PMID: 17151330

 

• de Borst MH, van Timmeren MM, Vaidya VS, de Boer RA, van Dalen MB, Kramer AB, Schuurs TA, Bonventre JV, Navis G, van Goor H. Induction of kidney injury molecule-1 in homozygous Ren2 rats is attenuated by blockade of the renin- angiotensin system or p38 MAP kinase. Am J Physiol Renal Physiol. 2007 Jan;292(1):F313-20. doi: 10.1152/ajprenal.00180.2006. Epub 2006 Aug 8. PMID: 16896183

 

• Pérez-Rojas J, Blanco JA, Cruz C, Trujillo J, Vaidya VS, Uribe N, Bonventre JV, Gamba G, Bobadilla NA. Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity. Am J Physiol Renal Physiol. 2007 Jan;292(1):F131-9. doi: 10.1152/ajprenal.00147.2006. Epub 2006 Jul 11. PMID: 16835406

2006

• Waikar SS, Bonventre JV. Can we rely on blood urea nitrogen as a biomarker to determine when to initiate dialysis? Clin J Am Soc Nephrol. 2006 Sep;1(5):903-4. doi: 10.2215/CJN.02560706. Epub 2006 Aug 16. PMID: 17699303

 

• Humphreys BD, Duffield JS, Bonventre JV. Renal stem cells in recovery from acute kidney injury. Minerva Urol Nefrol. 2006 Dec;58(4):329-37. PMID: 17268398

 

• Perianayagam MC, Liangos O, Kolyada AY, Wald R, MacKinnon RW, Li L, Rao M, Balakrishnan VS, Bonventre JV, Pereira BJ, Jaber BL. NADPH oxidase p22phox and catalase gene variants are associated with biomarkers of oxidative stress and adverse outcomes in acute renal failure. J Am Soc Nephrol. 2007 Jan;18(1):255-63. doi: 10.1681/ASN.2006070806. Epub 2006 Dec 6. PMID: 17151330

 

• Liu L, Zhao R, Bai Y, Stanish LF, Evans JE, Sanderson MJ, Bonventre JV, Rittenhouse AR. M1 muscarinic receptors inhibit L-type Ca2+ current and M-current by divergent signal transduction cascades. J Neurosci. 2006 Nov 8;26(45):11588-98. doi: 10.1523/JNEUROSCI.2102-06.2006. Erratum in: J Neurosci. 2006 Dec 6;26(49):12847. PMID: 17093080; PMCID: PMC6674797

 

• van de Weyer PS, Muehlfeit M, Klose C, Bonventre JV, Walz G, Kuehn EW. A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9. Biochem Biophys Res Commun. 2006 Dec 15;351(2):571-6. doi: 10.1016/j.bbrc.2006.10.079. Epub 2006 Oct 23. PMID: 17069754

 

• Duffield JS, Hong S, Vaidya VS, Lu Y, Fredman G, Serhan CN, Bonventre JV. Resolvin D series and protectin D1 mitigate acute kidney injury. J Immunol. 2006 Nov 1;177(9):5902-11. doi: 10.4049/jimmunol.177.9.5902. PMID: 17056514

 

• Vaidya VS, Bonventre JV. Mechanistic biomarkers for cytotoxic acute kidney injury. Expert Opin Drug Metab Toxicol. 2006 Oct;2(5):697-713. doi: 10.1517/17425255.2.5.697. PMID: 17014390

 

• Rennert PD, Ichimura T, Sizing ID, Bailly V, Li Z, Rennard R, McCoon P, Pablo L, Miklasz S, Tarilonte L, Bonventre JV. T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammation. J Immunol. 2006 Oct 1;177(7):4311-21. doi: 10.4049/jimmunol.177.7.4311. PMID: 16982865

 

• de Borst MH, van Timmeren MM, Vaidya VS, de Boer RA, van Dalen MB, Kramer AB, Schuurs TA, Bonventre JV, Navis G, van Goor H. Induction of kidney injury molecule-1 in homozygous Ren2 rats is attenuated by blockade of the renin-angiotensin system or p38 MAP kinase. Am J Physiol Renal Physiol. 2007 Jan;292(1):F313-20. doi: 10.1152/ajprenal.00180.2006. Epub 2006 Aug 8. PMID: 16896183

 

• Kang MS, Jeong JY, Seo JH, Jeon HJ, Jung KM, Chin MR, Moon CK, Bonventre JV, Jung SY, Kim DK. Methylmercury-induced toxicity is mediated by enhanced intracellular calcium through activation of phosphatidylcholine-specific phospholipase C. Toxicol Appl Pharmacol. 2006 Oct 15;216(2):206-15. doi: 10.1016/j.taap.2006.04.016. Epub 2006 May 19. PMID: 16854443

 

• Pérez-Rojas J, Blanco JA, Cruz C, Trujillo J, Vaidya VS, Uribe N, Bonventre JV, Gamba G, Bobadilla NA. Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity. Am J Physiol Renal Physiol. 2007 Jan;292(1):F131-9. doi: 10.1152/ajprenal.00147.2006. Epub 2006 Jul 11. PMID: 16835406

 

• Humphreys BD, Duffield JD, Bonventre JV. Renal stem cells in recovery from acute kidney injury. Minerva Urol Nefrol. 2006 Mar;58(1):13-21. Corrected and republished in: Minerva Urol Nefrol. 2006 Dec;58(4):329-37. PMID: 16760880

 

• Kim J, Kil IS, Seok YM, Yang ES, Kim DK, Lim DG, Park JW, Bonventre JV, Park KM. Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice. A role for manganese superoxide dismutase. J Biol Chem. 2006 Jul 21;281(29):20349-56. doi: 10.1074/jbc.M512740200. Epub 2006 May 8. PMID: 16682413

 

• van Timmeren MM, Bakker SJ, Vaidya VS, Bailly V, Schuurs TA, Damman J, Stegeman CA, Bonventre JV, van Goor H. Tubular kidney injury molecule-1 in protein-overload nephropathy. Am J Physiol Renal Physiol. 2006 Aug;291(2):F456-64. doi: 10.1152/ajprenal.00403.2005. Epub 2006 Feb 7. PMID:  16467126

 

• Meyer AM, Dwyer-Nield LD, Hurteau G, Keith RL, Ouyang Y, Freed BM, Kisley LR, Geraci MW, Bonventre JV, Nemenoff RA, Malkinson AM. Attenuation of the pulmonary inflammatory response following butylated hydroxytoluene treatment of cytosolic phospholipase A2 null mice. Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1260-6. doi: 10.1152/ajplung.00182.2005. Epub 2006 Jan 27. PMID: 16443645

 

• Balestrieri B, Hsu VW, Gilbert H, Leslie CC, Han WK, Bonventre JV, Arm JP. Group V secretory phospholipase A2 translocates to the phagosome after zymosan stimulation of mouse peritoneal macrophages and regulates phagocytosis. J Bio Chem. 2006 Mar 10;281(10):6691-8. doi: 10.1074/jbc.M508314200. Epub 2006 Jan 1.  PMID: 16407308; PMCID: PMC1820836

 

• Stafforini DM, Sheller JR, Blackwell TS, Sapirstein A, Yull FE, McIntyre TM, Bonventre JV, Prescott SM, Roberts LJ 2nd. Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet- activating factor acetylhydrolases. J Biol Chem. 2006 Feb 24;281(8):4616-23. doi: 10.1074/jbc.M507340200. Epub 2005 Dec 21. PMID: 16371369

 

• Vaidya VS, Ramirez V, Ichimura T, Bobadilla NA, Bonventre JV. Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury. Am J Physiol Renal Physiol. 2006 Feb;290(2):F517-29. doi: 10.1152/ajprenal.00291.2005. Epub 2005 Sep 20. PMID: 16174863

 

• Muckova K, Duffield JS, Held KD, Bonventre JV, Sheridan AM. cPLA2-interacting protein, PLIP, causes apoptosis and decreases G1 phase in mesangial cells. Am J Physiol Renal Physiol. 2006 Jan;290(1):F70-9. doi: 10.1152/ajprenal.00358.2004. Epub 2005 Jun 28. PMID: 15985650.\

2005

• Duffield JS, Tipping PG, Kipari T, Cailhier JF, Clay S, Lang R, Bonventre JV, Hughes J. Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. Am J Pathol. 2005 Nov;167(5):1207-19. doi: 10.1016/S0002-9440(10)61209-6. PMID: 16251406; PMCID: PMC1603796

 

• Vidal BC, Bonventre JV, I-Hong Hsu S. Towards the application of proteomics in renal disease diagnosis. Clin Sci (Lond). 2005 Nov;109(5):421-30. doi: 10.1042/CS20050085. PMID: 16232126

 

• Duffield JS, Bonventre JV. Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury. Kidney Int. 2005 Nov;68(5):1956-61. doi: 10.1111/j.1523-1755.2005.00629.x. PMID: 16221175; PMCID: PMC2915580

 

• Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol. 2005 Nov;16(11):3365-70. doi: 10.1681/ASN.2004090740. Epub 2005 Sep 21. PMID: 16177006

 

• Vaidya VS, Ramirez V, Ichimura T, Bobadilla NA, Bonventre JV. Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury. Am J Physiol Renal Physiol. 2006 Feb;290(2):F517-29. doi: 10.1152/ajprenal.00291.2005. Epub 2005 Sep 20. PMID: 16174863

 

• Hentschel DM, Bonventre JV. Novel non-rodent models of kidney disease. Curr Mol Med. 2005 Aug;5(5):537-46. doi: 10.2174/1566524054553469. PMID: 16101482

 

• Duffield JS, Park KM, Hsiao LL, Kelley VR, Scadden DT, Ichimura T, Bonventre JV. Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest. 2005 Jul;115(7):1743-55. doi: 10.1172/JCI22593. Epub 2005 Jun 2. PMID: 16007251; PMCID: PMC1159124

 

• Muckova K, Duffield JS, Held KD, Bonventre JV, Sheridan AM. cPLA2-interacting protein, PLIP, causes apoptosis and decreases G1 phase in mesangial cells. Am J Physiol Renal Physiol. 2006 Jan;290(1):F70-9. doi: 10.1152/ajprenal.00358.2004. Epub 2005 Jun 28. PMID: 15985650

 

• Ilsley JN, Nakanishi M, Flynn C, Belinsky GS, De Guise S, Adib JN, Dobrowsky RT, Bonventre JV, Rosenberg DW. Cytoplasmic phospholipase A2 deletion enhances colon tumorigenesis. Cancer Res. 2005 Apr 1;65(7):2636-43. doi: 10.1158/0008-5472.CAN-04-3446. PMID: 15805260

 

• Han WK, Alinani A, Wu CL, Michaelson D, Loda M, McGovern FJ, Thadhani R, Bonventre JV. Human kidney injury molecule-1 is a tissue and urinary tumor marker of renal cell carcinoma. J Am Soc Nephrol. 2005 Apr;16(4):1126-34. doi: 10.1681/ASN.2004070530. Epub 2005 Mar 2. PMID: 15744000; PMCID: PMC1307501

 

• Sapirstein A, Saito H, Texel SJ, Samad TA, O’Leary E, Bonventre JV. Cytosolic phospholipase A2alpha regulates induction of brain cyclooxygenase-2 in a mouse model of inflammation. Am J Physiol Regul Integr Comp Physiol. 2005 Jun;288(6):R1774-82. doi: 10.1152/ajpregu.00815.2004. Epub 2005 Feb 17. PMID: 15718387

 

• Lin J, Bonventre JV. Prevention of radiocontrast nephropathy. Curr Opin Nephrol Hypertens. 2005 Mar;14(2):105-10. doi: 10.1097/00041552-200503000-00004. PMID: 15687835

 

• Park KM, Cho HJ, Bonventre JV. Orchiectomy reduces susceptibility to renal ischemic injury: a role for heat shock proteins. Biochem Biophys Res Commun. 2005 Mar 4;328(1):312-7. doi: 10.1016/j.bbrc.2004.12.177. PMID: 15670785

 

• Hentschel DM, Park KM, Cilenti L, Zervos AS, Drummond I, Bonventre JV. Acute renal failure in zebrafish: a novel system to study a complex disease. Am J Physiol Renal Physiol. 2005 May;288(5):F923-9. doi: 10.1152/ajprenal.00386.2004. Epub 2004 Dec 29. Erratum in: Am J Physiol Renal Physiol. 2005 Oct;289(4):F939. PMID: 15625083

 

• Jaber BL, Pereira BJ, Bonventre JV, Balakrishnan VS. Polymorphism of host response genes: implications in the pathogenesis and treatment of acute renal failure. Kidney Int. 2005 Jan;67(1):14-33. doi: 10.1111/j.1523-1755.2005.00051.x. PMID: 15610224

 

• Cilenti L, Kyriazis GA, Soundarapandian MM, Stratico V, Yerkes A, Park KM, Sheridan AM, Alnemri ES, Bonventre JV, Zervos AS. Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells. Am J Physiol Renal Physiol. 2005 Feb;288(2):F371-9. doi: 10.1152/ajprenal.00154.2004. Epub 2004 Sep 28. PMID: 15454391.

2004

• Hentschel DM, Park KM, Cilenti L, Zervos AS, Drummond I, Bonventre JV. Acute renal failure in zebrafish: a novel system to study a complex disease. Am J Physiol Renal Physiol. 2005 May;288(5):F923-9. doi: 10.1152/ajprenal.00386.2004. Epub 2004 Dec 29. Erratum in: Am J Physiol Renal Physiol. 2005 Oct;289(4):F939. PMID: 15625083

 

• Han WK, Bonventre JV. Biologic markers for the early detection of acute kidney injury. Curr Opin Crit Care. 2004 Dec;10(6):476-82. doi: 10.1097/01.ccx.0000145095.90327.f2. PMID: 15616389

 

• Sim KG, Zang Z, Yang CM, Bonventre JV, Hsu SI. TRIP-Br links E2F to novel functions in the regulation of cyclin E expression during cell cycle progression and in the maintenance of genomic stability. Cell Cycle. 2004 Oct;3(10):1296-304. doi: 10.4161/cc.3.10.1157. Epub 2004 Oct 6. PMID: 15467469

 

• Cilenti L, Kyriazis GA, Soundarapandian MM, Stratico V, Yerkes A, Park KM, Sheridan AM, Alnemri ES, Bonventre JV, Zervos AS. Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells. Am J Physiol Renal Physiol. 2005 Feb;288(2):F371-9. doi: 10.1152/ajprenal.00154.2004. Epub 2004 Sep 28. PMID: 15454391

 

• Cilenti L, Soundarapandian MM, Kyriazis GA, Stratico V, Singh S, Gupta S, Bonventre JV, Alnemri ES, Zervos AS. Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death. J Biol Chem. 2004 Nov 26;279(48):50295-301. doi: 10.1074/jbc.M406006200. Epub 2004 Sep 15. PMID: 15371414

 

• Park KM, Kim JI, Ahn Y, Bonventre AJ, Bonventre JV. Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury. J Biol Chem. 2004 Dec 10;279(50):52282-92. doi: 10.1074/jbc.M407629200. Epub 2004 Sep 8. PMID: 15358759

 

• Bonventre JV. Pathophysiology of ischemic acute renal failure. Inflammation, lung-kidney cross-talk, and biomarkers. Contrib Nephrol. 2004;144:19-30. PMID: 15264395

 

• Bonventre JV, Zuk A. Ischemic acute renal failure: an inflammatory disease? Kidney Int. 2004 Aug;66(2):480-5. doi: 10.1111/j.1523-1755.2004.761_2.x. PMID: 15253693

 

• Thio SS, Bonventre JV, Hsu SI. The CtBP2 co-repressor is regulated by NADH- dependent dimerization and possesses a novel N-terminal repression domain. Nucleic Acids Res. 2004 Mar 22;32(5):1836-47. doi: 10.1093/nar/gkh344. PMID: 15037661; PMCID: PMC390340

 

• Meyer AM, Dwyer-Nield LD, Hurteau GJ, Keith RL, O’Leary E, You M, Bonventre JV, Nemenoff RA, Malkinson AM. Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2. Carcinogenesis. 2004 Aug;25(8):1517-24. doi: 10.1093/carcin/bgh150. Epub 2004 Mar 19. PMID: 15033900

 

• Luyckx VA, Bonventre JV. Dose of dialysis in acute renal failure. Semin Dial. 2004 Jan-Feb;17(1):30-6. doi: 10.1111/j.1525-139x.2004.17111.x. PMID: 14717809

 

• Ichimura T, Hung CC, Yang SA, Stevens JL, Bonventre JV. Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury. Am J Physiol Renal Physiol. 2004 Mar;286(3):F552-63. doi: 10.1152/ajprenal.00285.2002. Epub 2003 Nov 4. PMID: 14600030

 

• Ghosh M, Stewart A, Tucker DE, Bonventre JV, Murphy RC, Leslie CC. Role of cytosolic phospholipase A(2) in prostaglandin E(2) production by lung fibroblasts. Am J Respir Cell Mol Biol. 2004 Jan;30(1):91-100. doi: 10.1165/rcmb.2003-0005OC. Epub 2003 Jul 3. PMID: 12842849.

2003

• Bonventre JV. Molecular response to cytotoxic injury: role of inflammation, MAP kinases, and endoplasmic reticulum stress response. Semin Nephrol. 2003 Sep;23(5):439-48. doi: 10.1016/s0270-9295(03)00115-3. PMID: 13680533

 

• Andreucci M, Michael A, Kramers C, Park KM, Chen A, Matthaeus T, Alessandrini A, Haq S, Force T, Bonventre JV. Renal ischemia/reperfusion and ATP depletion/repletion in LLC-PK(1) cells result in phosphorylation of FKHR and FKHRL1. Kidney Int. 2003 Oct;64(4):1189-98. doi: 10.1046/j.1523-1755.2003.00204.x. PMID: 12969136

 

• Bonventre JV, Weinberg JM. Recent advances in the pathophysiology of ischemic acute renal failure. J Am Soc Nephrol. 2003 Aug;14(8):2199-210. doi:  10.1097/01.asn.0000079785.13922.f6. PMID: 12874476

 

• Haq S, Kilter H, Michael A, Tao J, O’Leary E, Sun XM, Walters B, Bhattacharya K, Chen X, Cui L, Andreucci M, Rosenzweig A, Guerrero JL, Patten R, Liao R, Molkentin J, Picard M, Bonventre JV, Force T. Deletion of cytosolic phospholipase A2 promotes striated muscle growth. Nat Med. 2003 Jul;9(7):944-51. doi: 10.1038/nm891. Erratum in: Nat Med. 2003 Sep;9(9):1221. PMID: 12808451

 

• Muñoz NM, Kim YJ, Meliton AY, Kim KP, Han SK, Boetticher E, O’Leary E, Myou S, Zhu X, Bonventre JV, Leff AR, Cho W. Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils. J Biol Chem. 2003 Oct 3;278(40):38813-20. doi: 10.1074/jbc.M302476200. Epub 2003 Jun 9. PMID: 12796497

 

• Bonventre JV. Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure. J Am Soc Nephrol. 2003 Jun;14 Suppl 1:S55-61. doi: 10.1097/01.asn.0000067652.51441.21. PMID: 12761240

 

• Hung CC, Ichimura T, Stevens JL, Bonventre JV. Protection of renal epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation. J Biol Chem. 2003 Aug 1;278(31):29317-26. doi: 10.1074/jbc.M302368200. Epub 2003 May 8. PMID: 12738790

 

• Li LF, Ouyang B, Choukroun G, Matyal R, Mascarenhas M, Jafari B, Bonventre JV, Force T, Quinn DA. Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-kappaB-inducing kinases. Am J Physiol Lung Cell Mol Physiol. 2003 Aug;285(2):L464-75. Doi 10.1152/ajplung.00031.2003. Epub 2003 Apr 25. PMID: 12716652

 

• Park KM, Byun JY, Kramers C, Kim JI, Huang PL, Bonventre JV. Inducible nitric-oxide synthase is an important contributor to prolonged protective effects of ischemic preconditioning in the mouse kidney. J Biol Chem. 2003 Jul 18;278(29):27256-66. doi: 10.1074/jbc.M301778200. Epub 2003 Apr 7. PMID: 12682064

 

• Han WK, Sapirstein A, Hung CC, Alessandrini A, Bonventre JV. Cross-talk between cytosolic phospholipase A2 alpha (cPLA2 alpha) and secretory phospholipase A2 (sPLA2) in hydrogen peroxide-induced arachidonic acid release in murine mesangial cells: sPLA2 regulates cPLA2 alpha activity that is responsible for arachidonic acid release. J Biol Chem. 2003 Jun 27;278(26):24153-63. doi: 10.1074/jbc.M300424200. Epub 2003 Apr 3. PMID: 12676927

 

• Choi WI, Quinn DA, Park KM, Moufarrej RK, Jafari B, Syrkina O, Bonventre JV, Hales CA. Systemic microvascular leak in an in vivo rat model of ventilator- induced lung injury. Am J Respir Crit Care Med. 2003 Jun 15;167(12):1627-32. doi: 10.1164/rccm.200210-1216OC. Epub 2003 Mar 27. PMID: 12663326

 

• Cilenti L, Lee Y, Hess S, Srinivasula S, Park KM, Junqueira D, Davis H, Bonventre JV, Alnemri ES, Zervos AS. Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2. J Biol Chem. 2003 Mar 28;278(13):11489-94. doi: 10.1074/jbc.M212819200. Epub 2003 Jan 15. PMID: 12529364

 

• Rosenberger TA, Villacreses NE, Contreras MA, Bonventre JV, Rapoport SI. Brain lipid metabolism in the cPLA2 knockout mouse. J Lipid Res. 2003 Jan;44(1):109-17. doi: 10.1194/jlr.m200298-jlr200. PMID: 12518029

2002

• Diaz BL, Fujishima H, Sapirstein A, Bonventre JV, Arm JP. Participation of cytosolic phospholipase A2 in eicosanoid generation by mouse bone marrow-derived mast cells. Adv Exp Med Biol. 2002;507:41-6. doi: 10.1007/978-1-4615-0193-0_7. PMID: 12664562

 

• Bonventre JV, Sapirstein A. Group IV cytosolic phospholipase A2 (PLA2) function: insights from the knockout mouse. Adv Exp Med Biol. 2002;507:25-31. doi: 10.1007/978-1-4615-0193-0_5. PMID: 12664560

 

• Heyman SN, Lieberthal W, Rogiers P, Bonventre JV. Animal models of acute tubular necrosis. Curr Opin Crit Care. 2002 Dec;8(6):526-34. doi: 10.1097/00075198-200212000-00008. PMID: 12454537

 

• Kuehn EW, Park KM, Somlo S, Bonventre JV. Kidney injury molecule-1 expression in murine polycystic kidney disease. Am J Physiol Renal Physiol. 2002 Dec;283(6):F1326-36. doi: 10.1152/ajprenal.00166.2002. Epub 2002 Jul 24. PMID: 12388382

 

• Goruppi S, Bonventre JV, Kyriakis JM. Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy. EMBO J. 2002 Oct 15;21(20):5427-36. doi: 10.1093/emboj/cdf535. PMID: 12374743; PMCID: PMC129067

 

• Bonventre JV. The kidney proteome: a hint of things to come. Kidney Int. 2002 Oct;62(4):1470-1. doi: 10.1111/j.1523-1755.2002.kid592.x. PMID: 12234321

 

• Bailly V, Zhang Z, Meier W, Cate R, Sanicola M, Bonventre JV. Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration. J Biol Chem. 2002 Oct 18;277(42):39739-48. doi: 10.1074/jbc.M200562200. Epub 2002 Jul 23. PMID: 12138159

 

• Auchincloss H, Bonventre JV. Transplanting cloned cells into therapeutic promise. Nat Biotechnol. 2002 Jul;20(7):665-6. doi: 10.1038/nbt0702-665. PMID: 12089546

 

• Han WK, Bailly V, Abichandani R, Thadhani R, Bonventre JV. Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int. 2002 Jul;62(1):237-44. doi: 10.1046/j.1523-1755.2002.00433.x. PMID: 12081583

 

• Song H, Lim H, Paria BC, Matsumoto H, Swift LL, Morrow J, Bonventre JV, Dey SK. Cytosolic phospholipase A2alpha is crucial [correction of A2alpha deficiency is crucial] for ‘on-time’ embryo implantation that directs subsequent development. Development. 2002 Jun;129(12):2879-89. Erratum in: Development 2002 Aug;129(15):3761. PMID: 12050136

 

• Ichinose F, Ullrich R, Sapirstein A, Jones RC, Bonventre JV, Serhan CN, Bloch KD, Zapol WM. Cytosolic phospholipase A(2) in hypoxic pulmonary vasoconstriction. J Clin Invest. 2002 Jun;109(11):1493-500. doi: 10.1172/JCI14294. PMID: 12045263; PMCID: PMC150993

 

• Gray ML, Bonventre JV. Training PhD researchers to translate science to clinical medicine: closing the gap from the other side. Nat Med. 2002 May;8(5):433-6. doi: 10.1038/nm0502-433. PMID: 11984576

 

• Kim SS, Chae HS, Bach JH, Lee MW, Kim KY, Lee WB, Jung YM, Bonventre JV, Suh YH. P53 mediates ceramide-induced apoptosis in SKN-SH cells. Oncogene. 2002 Mar 27;21(13):2020-8. doi: 10.1038/sj.onc.1205037. PMID: 11960374

 

• Bonventre JV. Daily hemodialysis–will treatment each day improve the outcome in patients with acute renal failure? N Engl J Med. 2002 Jan 31;346(5):362-4. doi: 10.1056/NEJM200201313460512. PMID: 11821514

 

• Bonventre JV. Kidney ischemic preconditioning. Curr Opin Nephrol Hypertens. 2002 Jan;11(1):43-8. doi: 10.1097/00041552-200201000-00007. PMID: 11753086

 

• Park KM, Kramers C, Vayssier-Taussat M, Chen A, Bonventre JV. Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction. J Biol Chem. 2002 Jan 18;277(3):2040-9. doi: 10.1074/jbc.M107525200. Epub 2001 Nov 5. PMID: 11696540

2001

• Panini SR, Yang L, Rusinol AE, Sinensky MS, Bonventre JV, Leslie CC. Arachidonate metabolism and the signaling pathway of induction of apoptosis by oxidized LDL/oxysterol. J Lipid Res. 2001 Oct;42(10):1678-86. PMID: 11590225

 

• Das A, Asatryan L, Reddy MA, Wass CA, Stins MF, Joshi S, Bonventre JV, Kim KS. Differential role of cytosolic phospholipase A2 in the invasion of brain microvascular endothelial cells by Escherichia coli and Listeria monocytogenes. J Infect Dis. 2001 Sep 15;184(6):732-7. doi: 10.1086/322986. Epub 2001 Aug 13. PMID: 11517434

 

• Namura S, Iihara K, Takami S, Nagata I, Kikuchi H, Matsushita K, Moskowitz MA, Bonventre JV, Alessandrini A. Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11569-74. doi: 10.1073/pnas.181213498. Epub 2001 Aug 14. PMID: 11504919; PMCID: PMC58770

 

• Bonventre JV. Complement and renal ischemia-reperfusion injury. Am J Kidney Dis. 2001 Aug;38(2):430-6. doi: 10.1053/ajkd.2001.26113. PMID: 11479175

 

• Sheridan AM, Force T, Yoon HJ, O’Leary E, Choukroun G, Taheri MR, Bonventre JV. PLIP, a novel splice variant of Tip60, interacts with group IV cytosolic phospholipase A(2), induces apoptosis, and potentiates prostaglandin production. Mol Cell Biol. 2001 Jul;21(14):4470-81. doi: 10.1128/MCB.21.14.4470-4481.2001. PMID: 11416127; PMCID: PMC87107

 

• Sheridan AM, Bonventre JV. Pathophysiology of ischemic acute renal failure. Contrib Nephrol. 2001;(132):7-21. doi: 10.1159/000060075. PMID: 11395913

 

• Sheridan AM, Sapirstein A, Lemieux N, Martin BD, Kim DK, Bonventre JV.Nuclear translocation of cytosolic phospholipase A2 is induced by ATP depletion. J Biol Chem. 2001 Aug 10;276(32):29899-905. doi: 10.1074/jbc.M103758200. Epub 2001 Jun 6. PMID: 11395512

 

• Zuk A, Bonventre JV, Matlin KS. Expression of fibronectin splice variants in the postischemic rat kidney. Am J Physiol Renal Physiol. 2001 Jun;280(6):F1037-53. doi: 10.1152/ajprenal.2001.280.6.F1037. PMID: 11352844

 

• Hsu SI, Yang CM, Sim KG, Hentschel DM, O’Leary E, Bonventre JV. TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1. EMBO J. 2001 May 1;20(9):2273-85. doi: 10.1093/emboj/20.9.2273. PMID: 11331592; PMCID: PMC125435

 

• Hong KH, Bonventre JC, O’Leary E, Bonventre JV, Lander ES. Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3935-9. doi: 10.1073/pnas.051635898. Epub 2001 Mar 13. PMID: 11274413; PMCID: PMC31157

 

• Samad TA, Moore KA, Sapirstein A, Billet S, Allchorne A, Poole S, Bonventre JV, Woolf CJ. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature. 2001 Mar. 22;410(6827):471-5. doi: 10.1038/35068566. PMID: 11260714

 

• Downey P, Sapirstein A, O’Leary E, Sun TX, Brown D, Bonventre JV. Renal concentrating defect in mice lacking group IV cytosolic phospholipase A(2). Am J Physiol Renal Physiol. 2001 Apr;280(4):F607-18. doi: 10.1152/ajprenal.2001.280.4.F607. PMID: 11249852

 

• Park KM, Chen A, Bonventre JV. Prevention of kidney ischemia/reperfusion-induced functional injury and JNK, p38, and MAPK kinase activation by remote ischemic pretreatment. J Biol Chem. 2001 Apr 13;276(15):11870-6. doi: 10.1074/jbc.M007518200. Epub 2001 Jan 9. PMID: 11150293

2000

• Faccio L, Chen A, Fusco C, Martinotti S, Bonventre JV, Zervos AS. Mxi2, a splice variant of p38 stress-activated kinase, is a distal nephron protein regulated with kidney ischemia. Am J Physiol Cell Physiol. 2000 Apr;278(4):C781-90. doi: 10.1152/ajpcell.2000.278.4.C781. PMID: 10751326

 

• Sapirstein A, Bonventre JV. Specific physiological roles of cytosolic phospholipase A(2) as defined by gene knockouts. Biochim Biophys Acta. 2000 Oct 31;1488(1-2):139-48. doi: 10.1016/s1388-1981(00)00116-5. PMID: 11080683

 

• Choukroun GJ, Marshansky V, Gustafson CE, McKee M, Hajjar RJ, Rosenzweig A, Brown D, Bonventre JV. Cytosolic phospholipase A(2) regulates golgi structure and modulates intracellular trafficking of membrane proteins. J Clin Invest. 2000 Oct;106(8):983-93. doi: 10.1172/JCI8914. PMID: 11032858; PMCID: PMC314339

 

• Sheridan AM, Bonventre JV. Cell biology and molecular mechanisms of injury in ischemic acute renal failure. Curr Opin Nephrol Hypertens. 2000 Jul;9(4):427-34. doi: 10.1097/00041552-200007000-00015. PMID: 10926180

 

• Sapirstein A, Bonventre JV. Phospholipases A2 in ischemic and toxic brain injury. Neurochem Res. 2000 May;25(5):745-53. doi: 10.1023/a:1007583708713. PMID: 10905638

 

• Gijón MA, Spencer DM, Siddiqi AR, Bonventre JV, Leslie CC. Cytosolic phospholipase A2 is required for macrophage arachidonic acid release by agonists that Do and Do not mobilize calcium. Novel role of mitogen-activated protein kinase pathways in cytosolic phospholipase A2 regulation. J Biol Chem. 2000 Jun 30;275(26):20146-56. doi: 10.1074/jbc.M908941199. PMID: 10867029

 

• Hsu SI, Ramirez SB, Winn MP, Bonventre JV, Owen WF. Evidence for genetic factors in the development and progression of IgA nephropathy. Kidney Int. 2000 May;57(5):1818-35. doi: 10.1046/j.1523-1755.2000.00032.x. PMID: 10792601

 

• Makkinje A, Quinn DA, Chen A, Cadilla CL, Force T, Bonventre JV, Kyriakis JM. Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent stress. J Biol Chem. 2000 Jun 9;275(23):17838-47. doi: 10.1074/jbc.M909735199. PMID: 10749885; PMCID: PMC3668664

 

• Welch DR, Sakamaki T, Pioquinto R, Leonard TO, Goldberg SF, Hon Q, Erikson RL, Rieber M, Rieber MS, Hicks DJ, Bonventre JV, Alessandrini A. Transfection of constitutively active mitogen-activated protein/extracellular signal-regulated kinase kinase confers tumorigenic and metastatic potentials to NIH3T3 cells. Cancer Res. 2000 Mar 15;60(6):1552-6. PMID: 10749122

 

• Faccio L, Fusco C, Chen A, Martinotti S, Bonventre JV, Zervos AS. Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia. J Biol Chem. 2000 Jan 28;275(4):2581-8. doi: 10.1074/jbc.275.4.2581. PMID: 10644717