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  1. Bonventre JV and Lechene C. A method for electron probe microanalysis of organic components in picoliter samples. Proceeding of the Microbeam Analysis Society, 9th Annual conference (Ottawa) 8A-8D, 1974.
  2. Beeuwkes R and Bonventre JV. Tubular organization and vascular-tubular relations in the dog kidney. American Journal of Physiology 229:695-713, 1975.
  3. Lechene C and Bonventre JV. Electron probe study of the urinary concentrating mechanism. Elemental cortico-papillary gradient in frozen hydrated rat kidney. Proceedings of the Microbeam Analysis Society, 11th Annual Conference (Miami) 61A-61G, 1976.
  4. Bonventre JV, Karnovsky MJ and Lechene CP. Renal papillary epithelial morphology in antidiuresis and water diuresis. American Journal of Physiology 235:F76-F76, 1978.
  5. Bonventre JV. Renal concentration mechanism: Role of papillary epithelium and pelvic urine; corticomedullary gradient by electron probe analysis; a passive model with functional heterogeneity in the outer medulla, Ph.D. Thesis, Harvard University 1979.
  6. Roman RJ, Bonventre JV and Lechene C. Fluorometric assay for urea in urine, plasma, and tubular fluid. Analytical Biochemistry 98:136-141 1979.
  7. Lechene C, Bonventre JV and Warner RR. Electron Probe analysis of frozen bulk tissues. In: Lechene C, Warner RR, eds. Microbeam Analysis in Biology. New York, Academic Press, pp. 409-423, 1979.
  8. Bonventre JV and Lechene C. Renal medullary concentration process: An integrative hypothesis. American Journal of Physiology 239:F578-F588, 1980.
  9. Bonventre JV, Roman R and Lechene C. Effect of the urea concentration of pelvic fluid on renal concentrating ability. American Journal of Physiology 239:F609-F618, 1980.
  10. Bonventre JV, Blouch K and Lechene C. Biological sample preparation for electron probe analysis: Liquid droplets and isolated cells. In: Hayat MA, ed. X-ray Microscopy in Biology. Baltimore University Park Press, pp307-366, 1980.
  11. Bonventre JV and Rabito CA. Electron microprobe analysis of cultured (LLC-PK1) renal epithelial cells. Proc Microbeam Analysis Society, 16th Annual Conference, 213-214, 1981.
  12. Roman RR, Bonventre JV, Silva P and Lechene C. Sodium orthovanadate diuresis in rats. J Pharm Exp Ther 218:168-174, 1981.
  13. Bonventre JV and Leaf A. Sodium homeostasis. Steady states without a set point. Kidney International. 21:880-885, 1981.
  14. Cheung JY, Thompson IG and Bonventre JV. Effects of extracellular calcium removal and anoxia on isolated rat myocytes. Am J Physiol 243 (Cell Physiol. 12):C184-C190, 1982.
  15. Jensen SR, Novelline RA, Brewster DC and Bonventre JV. Transient renal artery stenosis produced by a pheochromocytoma. Radiology 144:767-768, 1982.
  16. Bonventre JV. Key References in Nephrology, Churchill Livingston, Inc., New York, 1982. Book
  17. Lebowitz PQ, Cote ME, Daniels AL and Bonventre JV. Comparative renal effects of midazolam and thiopental in humans. Anesthesiology 59:381-384, 1983.
  18. Malis CD, Cheung JY, Leaf A and Bonventre JV. Effects of verapamil in models of ischemic acute renal failure in the rat. Am J. physiol. 245 (Renal Fluid Electrolyte Physiol. 14): F735-F742, 1983.
  19. Leaf A, Cheung JY, Mills JW and Bonventre JV. The nature of the cellular insult in acute renal failure. In: Acute Renal Failure, edited by B.M. Brenner and J.M. Lazarus, W.B. Saunders Co., pp. 2-20, 1983.
  20. Blackshear PJ, Nemenoff RA, Bonventre JV, Cheung JY and Avruch LA. Hormonal regulation of protein phosphorylation in isolated rat heart cells. Am J. Physiol. 246 (Cell Physiol 15):C439-449, 1984.
  21. Cheung JY, Leaf A and Bonventre JV. Mechanism of protection by verapamil and nifedipine from anoxic injury in isolated cardiac myocytes. Am J Physiol. 246 (Cell Physiol 15): C323-C329, 1984.
  22. Corwin and Bonventre JV. Renal insufficiency associated with nonsteroidal anti-inflammatory agents. Am J Kidney Diseases 4:147-152, 1984.
  23. Ausiello DA and Bonventre JV. Calcium and calmodulin as mediators of hormone action and transport events. Semin. Nephrol. 4:134-143, 1984.
  24. Bonventre JV. Cellular response to ischemia. In: Acute Renal Failure: Correlations between Morphology and function, eds. K. Soilez and A. Whelton, New York, Marcel Dekker, Inc., pp. 195-218. 1984.
  25. Bonventre JV and Cheung JY. Effects of metabolic acidosis on viability of cells exposed to anoxia. Am J physiol 250 (Cell Physiol. 18):C149-C159, 1985.
  26. Cheung JY, Leaf A and Bonventre JV. Determination of isolated myocyte viability. Staining methods and functional criteria. Basic Res Cardiol 80, Suppl. 1:23 – 30, 1985.
  27. Bonventre JV and Cheung JY. Cytosolic free calcium in cultured renal epithelial cells. Am J physiol. 250 (Renal Fluid Electrolyte Physiol 19):F329-F33, 1986.
  28. Bonventre JV, Skorecki EL, Kreisberg JI and Cheung JY. Vasopressin increases cytosolic free calcium concentration in glomerular mesangial cells. Am J Physiology 251 (Renal Fluid Electrolyte Physiol. 20):F94-F102, 1986.
  29. Cheung JY, Constantine JM and Bonventre JV. Regulation of cytosolic free calcium in cultured renal epithelial cells. Am J. physiol 251 (Renal, Fluid Electrolyte Physiol. 20):F690-F701, 1986.
  30. Cheung JY, Leaf A and Bonventre JV. Mitochondrial function and intracellular calcium in anoxic cardiac myocytes. Am J. Physiol. 250 (Cell Physiol 19):C18-C25, 1986.
  31. Diamond J., Bonventre JV and Karnovsky M. Oxygen free radicals and aminonucleoside nephrosis. Kidney International. 29:478-483., 1986.
  32. Malis CD and Bonventre JV. Mechanism of calcium potentiation of oxygen free radical injury to renal mitochondria. A model for post-ischemic and toxic mitochondrial damage. J Biol Chem 261:14201-14208, 1986.
  33. Cheung JY, Bonventre JV, malis CD and Leaf A. Calcium and ischemic injury. New Engl J Med. 324:1670-1676, 1986.
  34. Corwin HL and Bonventre JV. Acute Renal Faiulur. Med. Clinics NA. 70:1037-1054, 1986.
  35. Leaf A, MacKnight ADC, Cheung JY and Bonventre JV. The cellular basis of ischemic acute renal failure, in Physiology of Membrane Disorders, Andreoli TE, Hoffman JF, Fanestil DD and Schultz SG, eds. Plenum Medical Book Co., New York, 1986, pp. 769-784. Also in: Clinical Disorders of Membrane Transport Processes, 1986, pp. 3-18.
  36. Ara G, Aprille JR, Malis CO, Kane SB, Cincotta L, Foley J, Bonventre JV, and Oseroff AR. Mechanisms of mitochondrial photosensitization by a kryptocyanine dye: EDKC preferentially inactivates complex I in the electron transport chain. Cancer Res. 47:6580-6585, 1987.
  37. Ausiello DA, Skorecki, Verkman AS and Bonventre JV. Vasopressin signalling in kidney cells. Kidney Intl. 31:521-529, 1987.
  38. Cheung JY, Constantine JM and Bonventre JV. Cytosolic free calcium concentration and glucose transport in isolated cardiac myocytes. Am J Physiol 252 (Cell Physiol. 21):C163-172, 1987.
  39. Corwin HL, Schreiber MJ, Teplick R, Fang LST, Bonventre JV and Coggins CC. Prediction of outcome in acute renal failure. Am J nephrology 7:8-12, 1987.
  40. Malis CD and Bonventre JV. Susceptibility of mitochrondrial membranes to calcium and oxygen free radical damage. Potential modulation of injury by dietary n-3 fatty acids. Proceedings of the American Oil Chemists’ Society. Edited by W.E.M. lands, American oil Chemists’ Society, pp. 430-434, 1987.
  41. Bonventre JV, Weber P and Gronich J. PAF and PDGF increase cytosolic [Ca2+] and phospholipase activity in mesangial cells. Am J. Physiol. 254 (Renal Fluid Electrolyte Physiol. 23):F87-F94, 1988.
  42. Margolis BL, Bonventre JV, Kremer S, Kudlow JE and Skorecki KL. Epidermal growth factor is synergistic with phorbol esters and vasopressin in stimulating arachidonate release and prostaglandin production in renal glomerular mesangial cells. Biochemical Journal 249:587-592, 1988.
  43. Polla BS, Ohara J, Paul WE, Nabavi N, Myer A, Liou H-C, Shen F-W, Gillis 5, Bonventre JV and Glimcher LH. Differential induction of class II gene expression in murine pre-B-cell lines by B-cell stimulatory factor-I and antibodies to B-cell surface antigens. J Mol Cell Immunol. 3:363-373, 1988.
  44. Bonventre JV and Swidler M. Calcium dependency of prostaglandin E2 production in rat mesangial cells. Evidence that protein kinase C modulates the Ca2+-dependent activation of phospholipase A2 J Clin Invest. 82:168-176, 1988.
  45. Polla BS, Bonventre JV and Krane SM. 1,25-dihydroxyvitamin D3 increases the toxicity of hydrogen peroxide in the human monocyte line U937: role of calcium and heat shock. J Cell Biol. 107:373-380, 1988.
  46. Gronich JH, Bonventre JV and Nemenoff RA. Identification and characterization of a hormonally-regulated form of phospholipase A2 in rat renal mesangial cells. J Biol Chem 263:16645-16651, 1988.
  47. Lazarus JM, Kuritzkes DR and Bonventre JV. A 39-year-old woman with peripheral cyanosis, hypertension and acute renal failure. New Engl. J Med 318:234-242, 1988.
  48. Corwin HL and Bonventre JV. Acute Renal Failure in the intensive care unit. Intensive Care Medicine 14:10-16 (Part 1):86; 86-96 (Part 2), 1988.
  49. Bonventre JV. Mediators of ischemic renal injury. Ann Review of Medicine. 39:531-544, 1988.
  50. Bonventre JV, Leaf A and Malis CD. The Nature of the cellular insult in ischemic acute renal failure. In: Acute Renal Failure. B.M. Brenner and J.M. Lazarus, Eds. Churchill Livingstone, pp. 3-43, 1988.
  51. Bonventre JV. Vasopressin and calcium in cultured glomerular mesangial cells. In: Vasopressin: Cellular and Integrative Function, edited by AW Cowley, Jr., J-F Liard and DA Ausiello. Raven Press, pp. 89-96, 1988.
  52. Tolkoff-Rubin NE, Rubin RH and Bonventre JV. Non-invasive renal diagnostic studies. Clin Lab Med. 8:507-526, 1988.
  53. Malis CD and Bonventre JV. Susceptibility of mitochondrial membranes to calcium and reactive oxygen species: Implications for ischemic and toxic tissue damage. In: Biological Membranes: Aberrations in Membrane Structure and Function. ML Karnovsky, A Leaf and Bolis, eds. New York, Alan R. Liss, 1988, pp. 235-259, also In: Progress in Clinical and Biological Research 282:235-259, 1988.
  54. Force T, Malis CD, Guerrero JL, Varadarajan GS, Bonventre JV, Weber PC and Leaf A. n-3 Fatty acids increase post-ischemic blood flow but do not reduce myocardial necrosis. Am J Physiol. 257 (Heart Circ Physiol 26): H1204-H1210, 1989.
  55. Cybulsky AV, Salant DJ, Quigg RJ, Badalamenti J and Bonventre JV. Complement C5b-9 complex activates phospholipases in glomerular epithelial cells. Am J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F826-F836, 1989.
  56. Stafford-Brady F, Sugiyama E, Robinson DR, Sy M-S, Bonventre JV and Yeh ETH. Defective signal transduction in CD4-, CD8- T cells of lpr mice; Cellular Immunology, 123:396-404, 1989.
  57. Blochk D, Bonventre JV, Neer E and Seidman J. The G protein ao subunit alters morphology, growth kinetics and phospholipid metabolism of somatic cells. Mol. Cell Biol 9:5434-5439, 1989.
  58. Bonventre JV. Pathophysiologic pathways for renal injury. In: Textbook of Internal Medicine, 1st edition, edited by WN Kelley, JB Lippincott, pp. 743-748, 1989.
  59. Corwin HL and Bonventre JV. Factors influencing survival in acute renal failure. Sem. Dialysis 2:220-225, 1989.
  60. Ouellette AJ, malt RA, Sukhatme VP and Bonventre JV. Expression of two “Immediate Early” genes, egr-1 and c-fos, in response to renal ischemia and during compensatory renal hypertrophy in mice. J Clin Invest 85:766-771, 1990.
  61. Bonventre JV. Calcium in renal cells. Modulation of calcium dependent activation of phospholipase A2. Env. Health Persp. 84:155-162, 1990.
  62. Krane SM, Polla BS, and Bonventre JV. 1,25-dihydroxyvitamin D3 increases the toxicity of hydrogen peroxide: The role of calcium and heat shock. Experimental Gerontology. 25:239-245, 1990.
  63. Cybulsky AV, Bonventre JV, Quigg RJ, Wolfe IS and Salant DJ. Extracellular matrix regulates proliferation and phospholipid turnover in glomerular epithelial cells. Am J Physiol 259(Renal Fluid Electrolyte Physiol. 28):F236-F337, 1990.
  64. Bonventre JV, Gronich JH, and Nemenoff RA. Epidermal growth factor enhances glomerular mesangial cell soluble phospholipase A2 activity. J Biol Chem 265:4934-4938, 1990.
  65. Kantengwa S, Capponi AM, Bonventre JV, and Polla BS. Calcium and the heat shock response in the human monocyte line U937: Effects of 1,25-diydroxyvitamin D3. Am J Physiol 259 (Cell Physiol. 28):C77-C83, 1990.
  66. Reno TA, Ley S, Sugiyama E, Cantagrel A, Blumberg R, Bonventre JV, Terhorst C, and Yeh ETH. Generalized defects in signal transduction caused by a T-cell receptor b chain substitution. Eur J Immunol 20:1417-1422, 1990.
  67. Gronich JH, Bonventre JV and Nemenoff RA. Purification of a high-molecular-mass form of phospholipase A2 from rat kidney activated at physiological calcium concentration. Biochem J. 271:37-43, 1990.
  68. Cybulsky AV, Bonventre JV, Quigg RJ, Lieberthal W, and Salant DJ. Cytosolic calcium and protein kinase C modulate complement-mediated glomerular epithelial cell injury. Kidney Intl 38:803-811, 1990.
  69. Malis CD, Weber PC, leaf A and Bonventre JV. Incorporation of marine lipids into mitochondrial membranes increases susceptibility to damage by calcium and reactive oxygen species. Evidence for enhanced activation of phospholipase A2 in mitochondria enriched with n-3 fatty acids Proc Natl Acad Sci 87:8845-8849, 1990.
  70. Sugiyama E, Yeh ETH, Stafford-Brady F, Cantagrel A, Reno T and Bonventre JV. Characterization of T-cell receptor expression mutants derived by functional selection through T-cell activating protein. Cellular Immunology 130:271-280, 1990
  71. Bonventre JV, CD Malis and JY Cheung. Role of calcium in ischemic injury. In: Clinical Ischemic Syndromes. GB Zelenock, ed. C.V. Mosby Co., pp227-242, 1990.
  72. Bonventre JV. Calcium and the renal mesangial cell. In Calcium Antagonists and the Kidney. Edited by m. Epstein and R. Loutzenhiser. Hanley & Belfus, Inc., pp 87-105, 1990.
  73. Diamond JR and Bonventre JV. Ischemic acute renal failure. In: Principles and Practice of nephrology. Edited by HR Jacobson, GE Striker and S Klahr. Philadelphia: B.C. Decker, Inc., pp641-647, 1990.
  74. Sellmayer A, Uedelhoven WM, Weber PC and Bonventre JV. Endogenous non-cyclooxygenase metabolites of arachidonic acid modulate growth and mRNA levels of Immediate-Early response genes in rat mesangial cells. J. Biol. Chem. 266: 3800-3807, 1991.
  75. Force T, Hyman G, Hajjar R, Sellmayer A and Bonventre JV. Non-cyclooxygenase metabolites of arachidonate amplify the vasopressin-induced Ca2+ signal in glomerular mesangial cells by releasing Ca2+ from intracellular stores. J. Biol. Chem. 266: 4295-4302, 1991
  76. Force T, Kyriakis JM, Avruch J, and Bonventre JV. Endothelin, vasopressin, and angiotensin II enhance tyrosine phosphorylation by protein kinase C-dependent and-independent pathways in glomerular mesangial cells. J. Biol. Chem. 266: 6650-6656, 1991
  77. Bonventre JV, Sukhatme VP, Bamberger M, Ouellette A and Brown D. Localization of the protein product of the immediate early growth response gene, Egr-1, in the kidney after ischemia and reperfusion. Cell Regulation, 2: 251-260, 1991.
  78. Nakamura H, Nemenoff RA, Gronich JH and Bonventre JV. Subcellular characteristics of phospholipase A2 activity in rat kidney. Enhanced cytosolic, mitochondrial and microsomal phospholipase A2 enzymatic activity after renal ischemia and reperfusion. J. Clin. Invest. 87: 1810-1818, 1991.
  79. Rordorf G, Uemura Y and Bonventre JV. Characterization of phospholipase A2 (PLA2) activity in gerbil brain. Enhanced activities of cytosolic, mitochondrial and microsomal forms after ischemia and reperfusion. J. Neurosciences 11: 1829-1836, 1991.
  80. Malis CD, Varadarajan GS, Force T, Weber PC, Leaf A and Bonventre JV. Effects of dietary fish oils on vascular contractility subsequent to anoxia. Circulation 84:1393-1401, 1991.
  81. Polla BS., Mili N, and Bonventre JV. Les proteines de stress: quelles implications en nephrologie. Nephrologie 12: 119-123, 1991
  82. Hajjar RJ and Bonventre JV. Oscillations of intracellular calcium induced by vasopressin in individual fura-2-loaded mesangial cells. Frequency dependency on basal calcium concentration, agonist concentration and temperature. J. Biol. Chem. 266: 21589-21594, 1991
  83. Rordorf G, Koroshetz WJ, and Bonventre JV. Heat shock protects cultured neurons from glutamate toxicity. Neuron. 7:1043-1051, 1991.
  84. Bonventre JV and Colvin R. A 51-year-old man with severe hypertension and renal failure. New Engl J Med 325:563-572, 1991.
  85. Bonventre JV and Nemenoff RA. Renal tubular arachidonic acid metabolism. Kidney Intl. 39:438-119, 1991.
  86. Cybulsky AV and Bonventre JV. Calcium phospholipids and cell signaling. In: Hormones, Autocoids, and the Kidney. Contemporary Issues in nephrology. Edited by Goldfarb S and Ziyadeh FN. Pp 27-53, 1991.
  87. Bonventre JV. Pathophysiologic pathways for renal injury. In: Textbook of Internal Medicine, 2nd ed JB Lippincott, pp. 690-694, 1991.
  88. Sellmayer A, Krane SM, Ouellette AJ, and Bonventre JV. 1,25-(OH)2 Vitamin D3 induces expression of the genes encoding for two myeloid cell -specific calcium binding proteins, MRP-8 and MRP-14, in U937 cells. Am. J. Physiol. (Cell Physiol.) 262: C235-C242, 1992.
  89. Abou-Samra A-B, Juppner H, Force T, Freeman MW, Kong X-F, Schipani E, Urena P, Richards J, Bonventre JV, Potts Jr JT, Kronenberg HM, and Segre GV. Expression cloning of a PTH/PTHrP receptor from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc. Natl. Acad. Sci. USA. 89: 2732-2736, 1992.
  90. Force T, Bonventre JV, Flannery MR, Gorn AH, Yamin M, and Goldring SR. A cloned porcine renal calcitonin receptor couples to adenylyl cyclase and phospholipase C. Am. J. Physiol. (Renal Fluid and Electrolyte Physiol.) 262: F1110-F1115, 1992.
  91. Wong JT, Bonventre JV, Dunn S, and Colvin RB. Comparative studies of isolated CD3:CD8, CD3:CD3, and monovalent CD3 binding on CD8+ T-cell activation: Model of progressive T-cell receptor aggregation synergism. Human Immunol. 35: 200-208, 1992
  92. Segre GV, Abou-Samra A-B, Jüppner H, Schipani E, Force T, Urena P, Freeman M, Kong X-F, Kolakowski Jr. LF, Hock J, Bonventre JV, Potts JT, and Kronenberg HM. Characterization of cloned PTH/PTHrP receptors. J. Endocrinological Investigation 15, Suppl 6: 11-17, 1992.
  93. Bonventre JV. Passive calcium transport mechanisms. In: Membrane Transport in Biology, Vol. 5 Edited by Schafer JA, Ussing HH, Kristensen P, and Giebisch G. new York: Springer Verlag, PP 262-316, 1992
  94. Bonventre JV and Weinberg JM. Kidney preservation ex vivo for transplantation. Annu Rev Med 43:523-553, 1992.
  95. Bonventre JV. Phospholipase A2 and signal transduction. Jour. Am Soc neph 3:128-150, 1992.
  96. Cantiello HF, Prat AG, Bonventre JV, Cunningham CC, Hartwig JH, and Ausiello DA. Actin-binding protein contributes to cell volume regulatory ion channel activation in melanoma cells. J. Biol. Chem. 268: 4596-4599, 1993.
  97. Witzgall R, O’Leary E, Gessner R, Ouellette AJ, and Bonventre JV. Kid-1, a putative renal transcription factor: regulation during growth, ontogeny, and in response to ischemia and toxic injury. Mol. Cell. Biol. 13: 1933-1942, 1993.
  98. Bonventre, JV and Koroshetz WJ. Phospholipase A2 activity in Gerbil brain: Characterization of cytosolic and membrane-associated forms and effects of ischemia and reperfusion on enzymatic activity. J. Lipid Mediators. 6: 457-471, 1993.
  99. Kim DK and Bonventre JV. Purification of a 100 kDa phospholipase A2 from spleen, lung and kidney. Antiserum raised to porcine spleen phospholipase A2 recognizes a similar form in bovine lung, kidney and platelets and immunoprecipitates phospholipase A2 activity. Biochemical J. 294: 261-270, 1993.
  100. Kyriakis JM, Force T, Rapp UR, Bonventre JV, and Avruch J. Mitogen regulation of c-Raf-1 protein kinase activity toward mitogen-activated protein kinase. J. Biol. Chem. 268: 16009-16019, 1993.
  101. Bonventre JV. Mechanisms of ischemic acute renal failure (Nephrology Forum) Kidney Intl 43:1160-1178, 1993.
  102. Force T, Bonventre JV, Heidecker G, Rapp U, Avruch J, and Kyriakis JM. Enzymatic characteristics of the c-Raf-1 protein kinase. Proc. Natl. Acad. Sci. USA. 91: 1270-1274, 1994
  103. Kelly KJ, Williams Jr WW, Colvin RB, and Bonventre JV. Antibody to intercellular adhesion molecule-1 protects the kidney against ischemic injury. Proc Natl Acad Sci., USA 91:812-816, 1994.
  104. Force T, Bonventre JV, Heidecker G, Rapp U, Avruch J, and Kyriakis JM. Enzymatic characteristics of the c-Raf-1 protein kinase. Proc Natl Acad Sci USA 91:1270-1274, 1994.
  105. Witzgall R, Volk R, Yeung RS, and Bonventre JV. Genomic structure and chromosomal localization of the gene encoding the zinc finger transcription factor Kid-1. Genomics 20: 203-209, 1994.
  106. Witzgall R, Brown D, Schwarz C, and Bonventre JV. Localization of proliferating cell nuclear antigen, vimentin, c-Fos and clusterin in the postischemic kidney. Evidence for a heterogeneous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells. J. Clin. Invest. 93: 2175-2188, 1994.
  107. Witzgall R, O’Leary E, Leaf A, Önaldi D, and Bonventre JV. The KRAB-A domain of zinc finger proteins mediates transcriptional repression. Proc. Natl. Acad. Sci. USA. 91: 4514-4518, 1994.
  108. Lovis C, Mach F, Donati YRA, Bonventre JV, Polla BS. Heat shock proteins and the kidney. Renal Failure 16:179-192, 1994.
  109. Bonventre JV and Witzgall R. Cellular and molecular mechanisms of ischemic acute renal failure and repair. In: mechanisms of Injury in Renal Disease and Toxicity, edited by R.S. Goldstein and M.E. Davis. Telford Press, 1994, pp 15-42.
  110. Sohn UD, Kim DK, Bonventre JV, Behar J, and Biancani P. Role of 100-kDa cytosolic PLA2 in ACh-induced contraction of cat esophageal circular muscle. Am. J. Physiol. 267 (Gastrointest. Liver Physiol. 30): G433-G441, 1994.
  111. Rabb HA, Mendiok CC, Dietz J, Saba SR, Issekitz JB, Abanilla F, Bonventre JV, Ramirez G. Role of CD11a and CD11b in ischemic acute renal failure in rats. Amer J Physiol 267:F1052-1058, 1994.
  112. Abbate M, Bonventre JV, Brown D. The microtubule network of renal epithelial cells is disrupted by ischemia and reperfusion. Amer J Physiol 267:F971-F978, 1994.
  113. Pombo CM, Bonventre JV, Avruch J, Woodgett JR, Kyriakis JM, and Force T. The stress- activated protein kinases (SAPKs) are major c-jun amino-terminal kinases activated by ischemia and reperfusion. J. Biol. Chem. 269: 26546-26551, 1994.
  114. Witzgall R, O’Leary E, and Bonventre JV. A mammalian expression vector for the expression of GAL4-fusion proteins with an epitope tag and histidine tail. Anal. Biochem. 223: 291-298, 1994.
  115. Koroshetz WJ and Bonventre JV. Heat shock response in the central nervous system. Experientia 50:1085-1091, 1994.
  116. Saurina GR, and Bonventre JV. Acute renal failure. In: Conn’s Current Therapy. Ed by RE Rakel. Philadelphia: W.B. Saunders Company, pp. 635-641, 1995
  117. Nakamura H, Kim DK, Philbin DM, Peterson MB, Debros F, Koski G and Bonventre JV. Heparin-enhanced plasma phospholipase A2 activity and prostacyclin levels in patients undergoing cardiac surgery. J. Clin. Invest. 95: 1062-1070, 1995.
  118. Bonventre JV, Shah S, Walker PD, and Humphreys MH. Acute renal failure: ischemic, toxic, and other. In: Principles and Practice of Nephrology. Vol. 2 Edited by HR Jacobson, GE Striker and S Klahr. Philadelphia: B..C. Decker, inc. pp. 564-576, 1995.
  119. Bonventre JV, Kyriakis JM, Spech R, Witzgall R, Avruch J, and Force T. Phospholipase A2 and lipids as potential modulators of c-Raf-1 kinase. Amer. J. Therapeutics, 3: 287-293, 1996.
  120. Bonventre JV and Witzgall R. Kid-1, a kidney transcription factor. Exp. Nephrol. 3: 159-164, 1995.
  121. Ross BM, Kim DK, Bonventre JV, and Kish SJ. Characterization of a novel phospholipase A2 activity in human brain. J. Neurochemistry 64: 2213-2221, 1995.
  122. Kleinman JG, Worcester EM, Beshensky AM, Sheridan AM, Bonventre JV and Brown D. Upregulation of osteopontin expression by ischemia in rat kidney. Ann NY Acad Sci 760:321-323, 1995.
  123. Kim DK, Fukuda T, Thompson BT, Cockrill B, Hales C, and Bonventre JV. Bronchoalveolar lavage fluid phospholipase A2 activities are increased in human adult respiratory distress syndrome. Am J Physiol 269 (Lung Cell and Molecular Physiol. 13). L109-L118, 1995.
  124. Kim DK, Rordorf G, Nemenoff RA, Koroshetz WJ, and Bonventre JV. Glutamate stably enhances the activity of two cytosolic forms of phospholipase A2 rain cortical neurons. Biochem J 310:83-90, 1995.
  125. Rabb H, Mendiola CC, Saba SR, Dietz JR, Smith CW, Bonventre JV, Ramirez G. Antibodies to ICAM-1 protect kidneys in severe ischemic reperfusion injury. Biochem Biophys Res Comm 211:67-73, 1995.
  126. Bonventre JV. Phospholipases A2 In: Molecular Nephrology. Molecular Biology of the Kidney in Health and Disease, Edited by D. Schlondorff and JV Bonventre. New York: Marcel Dekker, Inc. pp. 681-697, 1995.
  127. Safirstein R and Bonventre JV. Molecular responses to ischemic and nephrotoxic acute renal failure. In: Molecular Nephrology molecular Biology of the Kidney in Health and Disease, Edited by D. Schlondorff and JV Bonventre. New York: Marcel Dekker, Inc. pp. 839-854, 1995.
  128. Witzgall R and Bonventre JV. Transcription factors in kidney development and renal injury. In: Molecular Nephrology. Molecular Biology of the Kidney in health and Disease, Edited by D. Schlondorff and JV Bonventre. New York: Marcel Dekker, Inc. pp. 535-550, 1995.
  129. Silverman ES, Thompson BT, Quinn DA, Kinane TB, Bonventre JV, and Hales CA. Na+/H+ exchange in pulmonary artery smooth muscle from spontaneously hypertensive rats and Wistar Kyoto rats. Am. J. Physiol. (Lung Cellular and Molecular Physiol.) 269(5 Pt 1):L673-80, 1995.
  130. Morooka H, Bonventre JV, Pombo CM, Kyriakis JM, and Force T. Ischemia and reperfusion enhance ATF-2 and c-Jun binding to cAMP response elements and to an AP-1 binding site from the c-jun promoter. J. Biol. Chem. 270:30084-30092, 1995.
  131. Bonventre JV and Kelly KJ. Adhesion molecules and acute renal failure. Advances in Nephrology 25:159-176, 1996
  132. Quinn DA, Dahlberg CGW, Bonventre JV, Scheid CR, Honeyman T, Joseph PM, Thompson BT, and Hales CA. The role of Na+/H+ exchange and growth factors in pulmonary artery smooth muscle proliferation. Am. J. Resp. Cell and Mol. Biol. 14: 139-145, 1996
  133. Dahlberg CGW, Thompson BT, Joseph PM, Garg HG, Spence CR, Quinn DA, Bonventre JV, and Hales CA. The differential effect of three commercial heparins on Na+/H+ exchange and growth of pulmonary artery smooth muscle cells. Am. J. Physiol. (Lung Cellular and Molecular Physiol.) 270: L260-265, 1996.
  134. Kelly KJ, Williams Jr. WW, Colvin RB, Meehan SM, Springer TA, Gutierrez-Ramos J-C, and Bonventre JV. Intercellular adhesion molecule-1 deficient mice are protected against ischemic renal injury. J Clin Invest 97:1056-1063, 1996.
  135. Bonventre JV. Calcium and calcium-related signalling pathways in glomerular mesangial cells. Clin Exp Pharmacol Physiol 23:65-70, 1996.
  136. Kelly KJ and Bonventre JV. Protection against ischemic renal injury with blockade of intercellular adhesion molecule-1. In: Acute Renal Failure, Edited by MS Goligorsky, New York: Churchill Livingstone. pp. 401-423, 1995.
  137. Bonventre JV. Phospholipases A2 in cell injury. In: Acute Renal Failure, Edited by MS Goligorsky, New York: Churchill Livingstone. Pp23-44.
  138. Thadhani R, Pascal M, and Bonventre JV. Acute renal failure New Eng J Med 334:1448-1460, 1996.
  139. Force T, Pombo CM, Avruch JA, Bonventre JV, and Kyriakis JM Stress-activated protein kinases in cardiovascular disease. Circulation 78:947-953, 1996
  140. Kelly DJ and Bonventre JV. Ischemia/reperfusion injury in transplantation. In: Transplantation Biology. Cellular and Molecular Aspects. Edited by NL Tilney, TB Strom and LC Paul. Raven Publishers, Philadelphia, 1996.
  141. Rothenberg ME, Ownbey R, Mehlhop PD, Loiselle PM, van de Rijn M, Bonventre JV, Oettegen HC, Leder P, and Luster AD. Eotaxin triggers eosinophil-selective chemotaxis and calcium flux via a distinct receptor and induces pulmonary eosinophilia in the presence of interleukin 5 in mice. Molecular Medicine 2:334-348, 1996.
  142. Sapirstein A, Spech RA, Witzgall R, and Bonventre JV. Cytosolic Phospholipase A2 (cPLA2), but not secretory PLA2, potentiates hydrogen peroxide cytotoxicity in kidney epithelial cells. J Biol Chem 271:21505-21513, 1996.
  143. Bonventre JV and Colvin RB. Adhesion molecules in renal disease. Curr. Opinion in Nephrology and Hypertension 5:254-261, 1996.
  144. Pombo CM, Kehrl JH, Sánchez I, Katz P, Avruch J, Zon LI, Woodgett JR, Force T, and Kyriakis JM. Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase. Nature 377: 750-754, 1996.
  145. Kelly JK, Tolkoff-Rubin NE, Rubin RH, Williams WW, Meehan SM, Meschter CL, Christenson JG, Bonventre JV. An oral platelet-activating factor antagonist, Ro-24-4736, protects the rat kidney from ischemic injury. Am J Physiol 271:F1061-F1067; 1996.
  146. Kim S-S, Chen Y-M, O’Leary E, Witzgall R, Vidal M, Bonventre JV. A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins. Proc Natl Acad Sci USA 93:15299-15304;1996.
  147. Bonventre JV. Roles of phospholipases A2 in brain cell and tissue injury associated with ischemia and excitotoxicity. J. Lipid Med. 16:199-208, 1997
  148. Chertow GM, Burke SK, Lazarus JM, Stenzek KH, Wombolt D, Goldberg D, Bonventre JV, Slatopolsky E. Poly [allylamine Hydrochloride] (RenaGel): A noncalcemic phosphate binder for the treatment of hyperphosphatemia in chronic renal failure. AJKD, 29:66-71, 1997.
  149. Witzgall R and Bonventre JV. Molecular responses to oxygen deprivation and ischemia. Molecular In: Comprehensive Toxicology Edited by G Sipes, CA McQueen, AJ Gandolfi Elsevier Science Ltd., 7:429-447, 1997.
  150. Pombo CM, Tsujita T, Kyriakis JM, Bonventre JV, Force T. Activation of the Ste20 like oxidant stress response kinase-1 during the initial stages of chemical anoxia-induced necrotic cell death. JBC, 272:29372-29379. 1997.
  151. Elser B, Kriz W, Bonventre JV, Englert C, Witzgall R. The Kruppel-associated box (KRAB)-zinc finger protein kid-1 and the Wilms’ tumor protein WT1, two transcriptional repressor proteins, bind to heteroduplex DNA. JBC 272:27908-27912. 1997.
  152. Thadhani RI and Bonventre JV. Acute Renal Failure. In: Quick Consult Manual of Evidence-Based Medicine. Edited by lee BW, Hsu SI, Stasior DS, Lippincott-Raven, 19:382-413, 1997.
  153. Bonventre JV, Huang Z, Taheri MR, O’Leary E, Li E, Moskowitz MA, Sapirstein A. Reduced fertility and post-ischemic brain injury in mice deficient in cytosolic phospholipase A2. Nature, 390:622-625, 1997.
  154. Brown D, Lee R, Bonventre JV. Redistribution of villin to proximal tubule basolateral membranes after ischemia and reperfusion. Amer Physiol Society 273: (Renal Physiol 42) F1003-F1011, 1997.
  155. DuBose TD Jr, Warnock DG, Mehta RL, Bonventre JV, Hammerman MR, Molitoris BA, Pallar MS, Siegel NJ, Scherbenske J, Striker GE. Acute renal failure in the 21st century: recommendations for management and outcomes assessment. AJKD 29:793-799, 1997.
  156. Bonventre JV. Arachidonic Acid Metabolism. In: Nephrology. Edited by Rex Jamison and Robert Wilkinson, Chapman and Hall 17:196-204, 1997.
  157. Ichimura T, Bonventre JV, Bailly v, Wei H, Hession CA, Cate RL, Sanicola M. Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. JBC, 273:4135-4142, 1998.
  158. Force T and Bonventre JV. Growth factors and mitogen-activated protein kinases. Hypertension 31:152-161, 1998.
  159. Bonventre JV. Role des molecules d’adhesion dans l’insuffisance renale aigue ischemique. Nephrologie 19:57-58, 1998.
  160. Bonventre JV, Force T. Mitogen-activated protein kinases and transcriptional responses in renal injury and repair. Curr Opin Nephrol Hypertens 7:425-433, 1998.
  161. Bonventre JV. Ischemic Acute Renal Failure. In: Principles of Molecular Medicine. Edited by J. Larry Jameson, Humana Press 66:651-657, 1998.
  162. Zuk A, Bonventre JV, Brown D, Matlin KS. Polarity, integrin, and extracellular matrix dynamics in the post-ischemic rat kidney. Am. J Physiol. 275 (3 Pt 1): C711-31, 1998
  163. Rabb H, Bonventre JV. Experimental strategies for acute renal failure: the future. In: Therapy in Nephrology and Hypertension; A Companion to Brenner and Rector’s The Kidney. Edited by Hugh R. Brady and Christopher S. Wilcox, W.B. Saunders Co. 12 : 71-80. 1998
  164. Bonventre JV. Pathogenetic and regenerative mechanisms in acute tubular necrosis, Kidney & Blood Pressure Research. 21:226-229, 1998
  165. Choukroun G, Hajjar R, Kyriakis J, Bonventre JV, Rosenzweig A, and Force T. Role of stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy. J Clin Invest. 102:1311-1320, 1998.
  166. Bonventre JV, Grevis M, Siegel S, Rosen D, Portilla D, and Venkatachalam M. Acute renal failure. I. Relative importance of proximal vs. distal tubular injury. Am. J. Physiol. F-623-F-632, 1998.
  167. Witzgall R, Obermuller N, Bolitz U, Calvet JP, Cowley BD Jr., Walker C, Kriz W, Gretz N, Bonventre JV. Kid-1 expression is high in differentiated renal proximal tubule cells and suppressed in cyst epithelia. Am J Physiol 275 (Renal Physiol. 44) F928-F937, 1998.
  168. Acute Renal Failure In: Atlas Disease of the Kidney. Edited by: T Berl and JV Bonventre. Current Medicine Vol. 1, 1998.
  169. Klivenyi P, Beal MF, Ferrante RJ, Andreassen OA, Werner M, Chin A-R, Bonventre JV. Mice Deficient in cytosolic phospholipase A2 are resistant to MPTP neurotoxicity. J Neurochem 71:2634-2637, 1998.
  170. Huang Z, Philippin B, O’Leary E, Bonventre JV, Kriz W, Witzgall R. Expression of the transcriptional repressor protein Kid-1 leads to the disintegration of the nucleus. J Bio Chem 274:7640-7648, 1999.
  171. Bonventre JV. The 85kD Cytosolic Phospholipase A2 knockout Mouse: A new Tool for physiology and cell biology J Am Soc Nephrol 10:404-412, 1999.
  172. Fujishima H, Sanchez Mejia, RO, Bingham CO, Lam BK, Sapirstein A, Bonventre JV, Austen KF, Arm JP. Cytosolic phospholipase A2 is essential for both the immediate and the delayed phases of eicosanoid generation in mouse bone marrow-derived mast cells. Proc Natl Acad Sci. USA. 96:4803-4807, 1999.
  173. Rabb Hamid, Bonventre JV, Leukocyte Adhesion Molecules in Transplantation. American Journal of Medicine, 107:157-165, 1999
  174. Kelly KJ, Meehan S, Colvin R, Williams, Jr. W, Bonventre JV, Protection from toxicant-mediated renal injury in the rat with anti-CD54 antibody, Kidney International, 3;56(3):922-931, 1999
  175. Abbate M., Brown D, Bonventre, JV, Expression of NCAM recapitulates tubulogenic development in kidneys recovering from acute ischemia. Am J Physiol. 277(3 Pt 2): F454-F463, 1999.
  176. Fukuda T, Kim DK, Chin MR, Hales C, Joseph V. Bonventre JV. Increased group IV cytosolic phospholipase A2 activity in lungs of sheep after smoke inhalation injury. Am J Physiol. 277(3 Pt 1): L533-L542, 1999.
  177. Alessandrini A, Namura S, Moskowitz MA, Bonventre JV. MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia. Proc. Natl. Acad. Sci. USA, 96 (no. 22): 12866-12869, 1999
  178. Mallouk, Y, Vayssier-Taussat, M, Bonventre, JV, Polla, B, Heat shock protein 70 and ATP as partners in cell Homeostasis (Review), Int’l Journal of Molecular Medicine 4: 463-474, 1999
  179. Tekki-Kessaris N, Bonventre J, Boulter C, Characterization of the mouse Kid1 gene and identification of a highly related gene, Kid2. Gene 240:13-22, 1999
  180. Faccio L, Fusco C, Chen Ang, Martinotti S, Bonventre JV, Zervos A, Characterization of a Novel Human Serine Protease That Has Extensive Homology to Bacterial Heat Shock Endoprotease HtrA and Is Regulated by Kidney Ischemia, J. of Biol. Chem, 275. 2581-2588, 2000
  181. Welch D, Sakamaki T, Pioquinto R, Leonard T, Goldberg S, Hon Q, Erikson R, Hicks D, Bonventre JV, Alessandrini A, Transfection of constitutively active Mek1 confers tumorigenic and metastatic potentials to NIH3T3 cells. Cancer Research, 60:1552-1556, 2000
  182. Faccio L, Chen A, Fusco C, Martinotti S, Bonventre JV, Zervos A, Mxi2, a splice variant of p38 stress-activated kinase, is a distal nephron protein regulated with kidney ischemia, Am J Physiol Cell Physiol, 278:781-790, 2000
  183. Sheridan A, Bonventre, JV. Cell Biology and molecular mechanisms of injury in ischemic acute renal failure, Curr Opin in Nephrol and Hypertens 9:427-434, 2000
  184. Hsu S-I, Ramirez S, Winn M, Bonventre JV, Owen W. Evidence for genetic factors in the development and progression of IgA nephropathy. Kidney Int 57: 1818-1835, 2000
  185. Gijon M, Spencer D, Siddiqui A, Bonventre JV, Leslie C. Cytosolic Phospholipase A2 Is Required For Machrophage Arachidonic Acid Release by Agonists that do and do not Mobilize Calcium. J. of Biol. Chem., 275:20146-20156, 2000
  186. Makkinje A, Quinn D, Chen A, Cadilla C, Force T, Bonventre JV, Kyriakis J. Gene 33/Mig-6; a transcriptionally-inducible Adapter Protein that Binds GTP-Cdc42 and Activates SAPK/JNK*. J. Biol. Chem. 275: 17838-17847,2000
  187. Sapirstein, A., Bonventre, JV., Phospholipase A2 in Ischemic and Toxic Brain Injury., Neurochem Res. 25:5 745-753,2000
  188. Bonventre, JV. Pathophsiology of ischemic acute renal failure. In: 6th Taormina Course on Nephrology, edited by Consolo F, Bellinghieri G, Savica, V. Editoriale Bios 49-53, 2000
  189. Choukroun, J, Marshansky V, Gustafson C, McKee M, Hajjar R, Rosenzweig, Brown D, Bonventre JV Cytosolic phospholipase A2 regulates Golgi structure and modulates intracellular trafficking of membrane proteins J. Clin. Invest., 106:983-993, 2000
  190. Force T, Alessandrini A, and Bonventre JV. Cell Signaling In: Kidney: Physiology and Pathophysiology, 3rd Edition. Edited by: Donald W. Seldin and Gerard Giebisch, Lippincott Williams & Wilkins 2000
  191. Sapirstein A, Bonventre JV. Specific physiological roles of cytosolic phospholipase A2 as defined by gene knockouts. Biochim Biophys Acta.1488:139-148, 2000
  192. Samad TA, Moore KA, Sapirstein A, Billet S, Allchorne A, Poole S, Bonventre JV, Woolf CJ. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature. 410:471-475, 2001
  193. Hong KH, Bonventre JC, O’Leary E, Bonventre JV, Lander ES. Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis. Proc Natl Acad Sci U S A. 98:3935-3939, 2001
  194. Downey P, Sapirstein A, O’Leary E, Sun T-X, Brown D, Bonventre, JV. Renal Concentrating Defect in Mice Lacking Group IV Cytosolic Phospholipase A2. Am. J. Physiol. Renal Physiol. 280:F607-F617, 2001
  195. Park, Kwon Moo, Chen A., and Bonventre, J.V.. Prevention of Kidney Ischemia/Reperfusion-induced Functional Injury and JNK, p38, and MAPK Kinase Activation by Remote Ischemic Pretreatment. Park KM, Chen A, Bonventre JV. J Biol Chem. 276:11870-11876, 2001
  196. Hsu, Stephen, Yang, Christopher Maolin, Sim, Khe Guan, Hentschel, Dirk M., O’Leary, Eileen, and Bonventre, J.V., TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1.EMBO J. 20:2273-2285, 2001
  197. Zuk A, Bonventre JV, Matlin KS. Expression of fibronectin splice variants in the postischemic rat kidney. Am J Physiol Renal Physiol. 280:1037-1053, 2001
  198. Sheridan AM, Force T, Yoon HJ, O’Leary E, Choukroun G, Taheri MR, Bonventre JV. Plip, a novel splice variant of tip60, interacts with group IV cytosolic phospholipase A2, induces apoptosis, and potentiates prostaglandin production. Mol Cell Biol. 21:4470-4481, 2001
  199. Sheridan AM, Sapirstein A, Lemieux N, Martin BD, Kim DK, Bonventre JV. Nuclear translocation of cPLA{sub2} is induced by ATP depletion. J Biol Chem. 276:29899-299905, 2001
  200. Bonventre, JV. Complement and Renal Ischemia-Reperfusion Injury. American Journal of Kidney Diseases. 38:430-436, 2001
  201. Das A, Asatryan L, Reddy MA, Wass CA, Stins MF, Joshi S, Bonventre JV, Kim KS. Differential role of cytosolic phospholipase A2 in the invasion of brain microvascular endothelial cells by Escherichia coli and Listeria monocytogenes. J Infect Dis. 184:732-737, 2001
  202. Namura S, Lihara K, Takami S, Nagata I, Kikuchi H, Matsushita K, Moskowitz M, Bonventre JV, Alessandrini A. Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia. PNAS. 98:2001
  203. Panini SR, Yang L, Rusinol AE, Sinensky MS, Bonventre JV, Leslie CC.. Arachidonate metabolism and the signaling pathway of induction of apoptosis by oxidized LDL/oxysterol. J Lipid Res. 42:1678-1686, 2001
  204. Schrier, RW and Eds. Essential Atlas of Nephrology, Philadelphia: Lippincott Williams & Wilkins Inc., 2001. (contains ch. 2 ed’d by JVB)
  205. Ichimura T and Bonventre JV. Growth factors, signaling, renal injury and repair. In Acute Renal Failure. Edited by B. Molitoris and W. Finn. WB Saunders, Inc. 2001
  206. Sheridan AM, Bonventre JV. Pathophysiology of ischemic acute renal failure. Contrib Nephrol. 132:7-21, 2001
  207. Bonventre, JV. Kidney ischemic preconditioning, Current Opinion in Nephrology and Hypertension 11:43-48 2002.
  208. Park KM, Kramers C, Vayssier-Taussat M, Chen A, Bonventre JV. Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction. J Biol Chem. 277:2040-2049, 2002
  209. Bonventre, JV. Daily Hemodialysis-Will Treatment Each Day improve The Outcome In Patients with Acute Renal Failure? NEJM Editorial, Daily Dialysis, 2002
  210. Han WK, Bailly V, Abichandani R, Thadhani R, Bonventre JV. Kidney Injury Molecule- 1 (KIM-1): A novel biomarker for human renal proximal tubule injury. Kidney International 62:237-244, 2002
  211. Kim SS, Chae HS, Bach JH, Lee MW, Kim KY, Lee WB, Jung YM, Bonventre JV, Suh YH. P53 mediates ceramide-induced apoptosis in SKN-SH cells. Oncogene;21:2020-2028, 2002
  212. Gray ML, Bonventre JV. Training PhD researchers to translate science to clinical medicine. Closing the gap from the other side. Nat Med. 8; 433-436. 2002
  213. Ichinose F, Ullrich R, Sapirstein A, Jones RC, Bonventre JV, Serhan CN, Bloch KD, Zapol WM. Cytosolic phospholipase A(2) in hypoxic pulmonary vasoconstriction. Journal of Clinical Investigation;109:1493-1500 2002
  214. Song H, Lim H, Paria BC, Matsumoto H, Swift LL, Morrow J, Bonventre JV, Dey SK. Cytosolic phospholipase A(2)alpha deficiency is crucial for ‘on-time’ embryo implantation that directs subsequent development. Development;129:2879-2889 2002
  215. Auchincloss H, Bonventre JV. Transplanting cloned cells into therapeutic promise. Nature Biotechnology;7:665-666 2002
  216. Goruppi S, Bonventre JV, Kyriakis, JM. Signaling Pathways and Late-Onset Gene Induction Associated with Renal Mesangial Cell Hypertrophy. EMBO Journal; 21:5427-5436, 2002
  217. Bonventre JV, The kidney proteome: a hint of things to come. Kidney International 62;1470-1471, 2002
  218. Bailly V, Zhang Z, Meier W, Cate R, Sanicola M, Bonventre JV. Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration. J Biol Chem. 277: 39739-39748, 2002
  219. Heyman SN, Lieberthal W, Rogiers P, Bonventre JV. Animal models of acute tubular necrosis. Curr Opin Crit Care. 8:526-534, 2002.
  220. Kuehn EW, Park KM, Somlo S, Bonventre JV. Kidney injury molecule-1 expression in murine polycystic kidney disease. Am J Physiol Renal Physiol;283(6):F1326-1336, 2002
  221. Bonventre JV, Sapirstein A. Group IV cytosolic phospholipase A2 (PLA2) function: insights from the knockout mouse. Adv Exp Med Biol 507:25-31, 2002
  222. Diaz BL, Fujishima H, Sapirstein A, Bonventre JV, Arm JP. Participation of cytosolic phospholipase A2 in eicosanoid generation by mouse bone marrow-derived mast cells. Adv Exp Med Biol 507:41-46, 2002
  223. Rosenberger TA, Villacreses NE, Contreras MA, Bonventre JV, Rapoport SI. Brain lipid metabolism in the cPLA2 knockout mouse. The Journal of Lipid Research 44:109-117, 2003
  224. Cilenti L, Lee Y, Hess S, Srinivasula S, Park KM, Junqueira D, Davis H, Bonventre JV, Alnemri ES, Zervos AS. Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2. J Biol Chem 278:11489-11494, 2003
  225. Choi WI, Quinn DA, Park KM, Moufarrej RK, Jafari B, Syrkina O, Bonventre JV, Hales CA. Systemic microvascular leak in an in vivo rat model of ventilator-induced lung injury. Am J Respir Crit Care Med 167:1627-1632, 2003
  226. Han WK, Sapirstein A, Hung CC, Alessandrini A, Bonventre JV. Cross-talk between cytosolic phospholipase A2 alpha (cPLA2 alpha) and secretory phospholipase A2 (sPLA2) in hydrogen peroxide-induced arachidonic acid release in murine mesangial cells: sPLA2 regulates cPLA2 alpha activity that is responsible for arachidonic acid release. J Biol Chem 278:24153-24163, 2003
  227. Park KM, Byun JY, Kramers C, Kim JI, Huang PL, Bonventre JV. Inducible nitric-oxide synthase is an important contributor to prolonged protective effects of ischemic preconditioning in the mouse kidney. J Biol Chem 278:27256-27266, 2003
  228. Li LF, Ouyang B, Choukroun G, Matyal R, Mascarenhas M, Jafari B, Bonventre JV, Force T, Quinn DA. Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-κB-inducing kinases. Am J Physiol Lung Cell Mol Physiol 285:L464-L475, 2003
  229. Hung CC, Takaharu I, Stevens JL, Bonventre JV. Protection of renal Epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation. J Biol Chem 278:29317-29326, 2003
  230. Bonventre JV. Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure. J Am Soc Nephrol 14:S55-61, 2003
  231. Munoz NM, Kim YJ, Meliton AY, Kim KP, Han SK, Boetticher E, O’Leary E, MyouS, Xu X, Bonventre JV, Leff AR, Cho W. Human group V phospholipase A2 induces group IVA phospholipase A2-independ entcysteinyl leukotriene synthesis in human Eosinophils. J Biol Chem 278:38813-38820, 2003
  232. Haq S, Kilter H, Michael A, Tao J, O’Leary E, Sun XM, Walters B, Bhattacharya K, Chen X, Cui L, Andreucci M, Rosenzweig A, Guerrero JL, Patten R, Liao R, Molkentin J, Picard M, Bonventre JV, Force T. Deletion of cytosolic phospholipase A(2) promotes striated muscle growth. Nat Med 9:944-951, 2003
  233. Bonventre JV, Weinberg JM. Recent advances in the pathophysiology of ischemic acute renal failure. J Am Soc Nephrol 14:2199-2210, 2003
  234. Andreucci M, Michael A, Kramers C, Park KM, Chen A, Matthaeus T, Alessandrini A, Qaq S, Force F, Bonventre JV. Renal ischemia/reperfusion and ATP depletion/repletion in LLC-PK1 cells result in phosphorylation of FKHRL1. Kidney International 64:1189-1198, 2003
  235. Bonventre JV. Molecular Response to Cytotoxic Injury: Role of Inflammation, MAP Kinases, and Endoplasmic Reticulum Stress Response. Seminars in Nephrology 23:439-448, 2003
  236. Ghosh M, Stewart A, Tucker DE, Bonventre JV, Murphy RC, Leslie CC. Role of cytosolic phospholipase A2 in prostaglandin E2 production by lung fibroblasts. Am J Respir Cell Mol Biol 30:91-100, 2003
  237. Ichimura T, Hung CC, Yang SA, Stevens JL, Bonventre JV, Kidney Injury Molecule-1 (Kim –1): A Tissue and Urinary Biomarker for Nephrotoxicant-Induced Renal Injury. American J of Physio 286:F552-563, 2004
  238. Luyckx VA, Bonventre JV. Dose of dialysis in acute renal failure. Semin Dial 17:30-36, 2004
  239. Meyer AM, Dwyer-Nield LD, Hurteau GJ, Keith RL, O’Leary E, You M, Bonventre JV, Nemenoff RA, Malkinson AM. Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2. Carcinogenesis 8:1517-24, 2004
  240. Thio SS, Bonventre JV, Hsu SI. The CtBP2 co-repressor is regulated by NADH-dependent dimerization and possesses a novel N-terminal repression domain. Nucleic Acids Res 32(5):1836-1847, 2004
  241. Bonventre JV. Cytosolic phospholipase A2α reigns supreme in arthritis and bone resoption. Trends Immunol 25:116-119, 2004
  242. Bonventre JV, Zuk A. Ischemic Acute Renal Failure: An Inflammatory Disease? Kidney Int 66: 480-485, 2004
  243. De Broe ME, Bonventre JV, Molitoris BA, Haller H. Evolving basic concepts in ischemic injury, Kidney Int 66:479, 2004
  244. Bonventre, JV. Pathophysiology of Ischemic Acute Renal Failure: Inflammation, Lung-Kidney Cross-talk, and Biomarkers. Contrib Nephrol 144:19-30, 2004
  245. Park KM, Kim JI, Ahn Y, Bonventre AJ, Bonventre JV. Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury. J Biol Chem 279(50):52282-92, 2004
  246. Cilenti L, Kyriazis GA, Soundarapandian MM, Stratico V, Yerkes A, Park KM, Sheridan AM, Alnemri ES, Bonventre JV, Zervos AS. Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells. Am J Physiol Renal Physiol 288(2):F371-9, 2005
  247. Cilenti L, Soundarapandian MM, Kyriazis GA, Stratico V, Singh S, Gupta S, Bonventre JV, Alnemri ES, Zervos AS. Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death. J Biol Chem 279(48):50295-301, 2004
  248. Sim KG, Zang Z, Yang CM, Bonventre JV, Hsu SI. TRIP-Br Links E2F to Novel Functions in the Regulation of Cyclin E Expression During Cell Cycle Progression and in the Maintenance of Genomic Stability. Cell Cycle 3(10):1296-304, 2004
  249. Jaber BL, Pereira BJ, Bonventre JV, Balakrishnan VS. Polymorphism of host response genes: implications in the pathogenesis and treatment of acute renal failure. Kidney Int 67(1):14-33, 2005
  250. Han WK, Bonventre JV. Biologic markers for the early detection of acute kidney injury. Curr Opin Crit Care 10(6):476-482, 2004
  251. Hentschel DM, Park KM, Cilenti L, Zervos AS, Drummond I, Bonventre JV. Acute Renal Failure in Zebrafish: A Novel System to Study a Complex Disease. Am J Physiol Renal Physiol 288(5):F923-9, 2004
  252. Park KM, Cho HJ, Bonventre JV. Orchiectomy reduces susceptibility to renal ischemic injury: a role for heat shock proteins. Biochem Biophys Res Commun 4;328(1):312-7, 2005
  253. Lin J, Bonventre JV. Prevention of radiocontrast nephropathy. Curr Opin Nephrol Hypertens 14(2):105-110, 2005
  254. Sapirstein A, Saito H, Texel S, Samad T, O’leary E, Bonventre JV. Cytosolic Phospholipase A2α Regulates Induction Of Brain Cyclooxygenase-2 In a Mouse Model of Inflammation. Am J Physiol Regul Integr Comp Physiol;288(6):R1774-82, Jun 2005
  255. Han WK, Alinani A, Wu CL, Michaelson D, Loda M, McGovern FJ, Thadhani R, Bonventre JV. Human Kidney Injury Molecule-1 Is a Tissue and Urinary Tumor Marker of Renal Cell Carcinoma. J Am Soc Nephrol 16(4):1126-34, 2005
  256. Ilsley JN, Nakanishi M, Flynn C, Belinsky GS, De Guise S, Adib JN, Dobrowsky RT, Bonventre JV, Rosenberg DW. Cytoplasmic phospholipase A2 deletion enhances colon tumorigenesis. Cancer Res. ;65(7):2636-43, 2005
  257. Muckova K, Duffield JS, Held KD, Bonventre JV, Sheridan AM. cPLA2-interacting protein, PLIP, causes apoptosis and decreases G1 phase in mesangial cells. Am J Physiol Renal Physiol.;290(1):F70-9, 2006
  258. Duffield JS, Park KM, Hsiao LL, Kelley VR, Scadden DT, Ichimura T, Bonventre JV. Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest.;115(7):1743-55, 2005
  259. Duffield, J S., Bonventre JV. Acute Renal Failure: Bench to Bedside. In: Chronic Kidney Disease, Dialysis, and Transplantation; A companion to Brenner and Rector’s The Kidney. Edited by Pereira Brian JG, Sayegh MH, Blake Peter, New Jersey: Elsevier, Inc., pp 765-786, 2005
  260. Vaidya VS, Ramirez V, Ichimura T, Bobadilla NA, Bonventre JV. Urinary kidney injury molecule-1 (kim-1): a sensitive quantitative biomarker for early detection of kidney tubular injury. Am J Physiol Renal Physiol. 290 (2): F517, 2006
  261. Curr Mol Med.;5(5):537-46, 2005
  262. Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol.;16(11):3365-70, 2005
  263. Duffield JS and Bonventre JV. Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury. Kidney Int.;68(5):1956-61, 2005
  264. Vidal BC, Bonventre JV and Hsu S IH. Towards the Application of Proteomics in Renal Disease Diagnosis. Review. Clin Sci;109(5):421-30, 2005
  265. Duffield JS, Tipping PG, Kipari T, Cailhier JF, Clay S, Lang R, Bonventre JV, Hughes J. Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. Am J Pathol.;167(5):1207-19, 2005
  266. Bellomo R, Bonventre J, Macias W, Pinsky M. Management of early acute renal failure: focus on post-injury prevention. Curr Opin Crit Care.;11(6):542-547, 2005
  267. Stafforini DM, Sheller JR, Blackwell TS, Sapirstein A, Yull FE, McIntyre TM, Bonventre JV, Prescott SM, Roberts LJ 2nd. Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases. J Biol Chem. Feb 21;281(8):4616-23, 2006.
  268. Balestrieri B, Hsu VW, Gilbert H, Leslie CC, Han WK, Bonventre JV, Arm JP.Group V secretory phospholipase A2 translocates to the phagosome after zymosan stimulation of mouse peritoneal macrophages and regulates phagocytosis. J Biol Chem. Mar;10281(10):6691-8, 2006.
  269. Meyer AM, Dwyer-Nield LD, Hurteau G, Keith RL, Ouyang Y, Freed BM, Kisley LR, Geraci MW, Bonventre JV, Nemenoff RA, Malkinson AM. Attenuation of the pulmonary inflammatory response following butylated hydroxytoluene (BHT) treatment of cytosolic phospholipase A2 (cPLA2) null mice. Am J Physiol Lung Cell Mol Physiol. Jun;290(6):L1260-6, 2006.
  270. van Timmeren MM, Bakker SJ, Vaidya VS, Bailly V, Schuurs TA, Damman J, Stegeman CA, Bonventre JV, van Goor H. Tubular Kidney Injury Molecule-1 (Kim-1) In Protein-Overload Nephropathy. Am J Physiol Renal Physiol. 2006 Aug;291(2):F456-64. 2006
  271. Hung, CC and Bonventre, JV. Acute kidney injury. In: Educational Review Manual in Nephrology. In press.
  272. Humphreys, BD, Duffield JS and Bonventre JV. Renal Stem Cells in recovery from Acute Kidney Injury. Minerva Urol Nephrol.58(1):13-21, 2006.
  273. Kim J, Kil IS, Seok YM, Yang ES, Kim DK, Lim DG, Park JW, Bonventre JV, Park KM. Orchiectomy attenuates post-ischemic oxidative stress andischemia/reperfusion injury in mice. A role for manganese superoxide dismutase. J Biol Chem. 2006 Jul 21;281(29):20349-56.
  274. Perez-Rojas J, Blanco JA, Cruz C, Trujillo J, Vaidya VS, Uribe N, Bonventre JV, Gamba G, Bobadilla NA. Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity. Am J Physiol Renal Physiol. Epub. July 2006. In press.
  275. Kang MS, Jeong JY, Seo JH, Jeon HJ, Jung KM, Chin MR, Moon CK, Bonventre JV, Jung SY, Kim DK. Methylmercury-induced toxicity is mediated by enhanced intracellular calcium through activation of phosphatidylcholine-specific phospholipase C. Toxicol Appl Pharmacol. 2006 Oct 15;216(2):206-15.
  276. De Borst MH, van Timmeren MM, Vaidya VS, Van Dalen MB, Kramer AB, Schuurs TA, Bonventre JV, Navis G, van Goor H. Induction of Kidney injury molecule-1 (Kim-1) in homozygous Ren2 rats is attenuated by blockade of the renin-angiotensin system or p38 MAP kinase. Am J Physiol Renal Physiol. Epub. Aug 8 2006. In press.
  277. Lin F, Zhang P, Yang XJ, Blasick TM, Han WK, Shen SS, Bonventre JV. Human Kidney Injury Molecule-1 (hKIM-1): A Useful Immunohistochemical Marker for Diagnosing Renal Cell Carcinoma and Ovarian Clear Cell Carcinoma. Am J Surg Pathol. In press.
  278. Vaidya VS, Bonventre JV. Mechanistic biomarkers for cytotoxic acute kidney injury.Expert Opin Drug Metab Toxicol. 2006 Oct;2(5):697-713.
  279. Lechene CP, Hillion F, McMahon G, Benson DM, Kleinfeld AM, Kampf JP, Distel DL, Luyten YA, Bonventre JV, Hentschel DM, Park KM, Ito S, Schwartz MA, Benichou GA, Slodzian G. High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry. J Biol. 2006 Oct 5;5(6):20
  280. Rennert PD, Ichimura T, Sizing ID, Bailly V, Li Z, Rennard R, McCoon P, Pablo L, Miklasz S, Tarilonte L, Bonventre JV. T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of th2 immune responses and airway inflammation. J Immunol. 2006 Oct 1;177(7):4311-21.
  281. Duffield JS, Hong S, Vaidya VS, Lu Y, Fredman G, Serhan CN, Bonventre JV. Resolvin D Series and Protectin D1 Mitigate Acute Kidney Injury. J Immunol. 2006 Nov 1;177(9):5902-5911.
  282. Duffield, JS and Boventre JV. Response to: “Could tubular interstitium be a source of adult epithelial stem cells?”. In press.
  283. Waikar SS and Bonventre JV. Can we rely on Blood Urea Nitrogen as a biomarker to determine when to initiate dialysis? Clin J Am Soc Nephrol. 1(5): 903-904. 2006

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